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Severe Mycoplasma pneumonia in three sisters with sickle cell disease.

Publication ,  Journal Article
Becton, DL; Friedman, HS; Kurtzberg, J; Chaffee, S; Falletta, JM; Kinney, TR
Published in: Pediatr Hematol Oncol
1986

Mycoplasma pneumoniae, which usually causes mild infections in normal children, has been shown to cause isolated cases of severe pneumonia in children with sickle cell disease. We recently observed an outbreak of Mycoplasma pneumonia in three sisters with homozygous sickle cell disease. Two of them required hospitalization, and one progressed to respiratory failure requiring prolonged ventilatory assistance. All eventually recovered without long-term pulmonary complications. Familial outbreaks are not uncommon in Mycoplasma infection, but they have not been described previously in siblings with sickle cell disease. It is assumed that local or systemic host defense abnormalities predispose patients with sickling syndromes to more severe courses of Mycoplasma infections.

Duke Scholars

Published In

Pediatr Hematol Oncol

DOI

ISSN

0888-0018

Publication Date

1986

Volume

3

Issue

3

Start / End Page

259 / 265

Location

England

Related Subject Headings

  • Radiography
  • Pneumonia, Mycoplasma
  • Pleural Effusion
  • Oncology & Carcinogenesis
  • Humans
  • Female
  • Family
  • Combined Modality Therapy
  • Child
  • Anemia, Sickle Cell
 

Citation

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Becton, D. L., Friedman, H. S., Kurtzberg, J., Chaffee, S., Falletta, J. M., & Kinney, T. R. (1986). Severe Mycoplasma pneumonia in three sisters with sickle cell disease. Pediatr Hematol Oncol, 3(3), 259–265. https://doi.org/10.3109/08880018609031225
Becton, D. L., H. S. Friedman, J. Kurtzberg, S. Chaffee, J. M. Falletta, and T. R. Kinney. “Severe Mycoplasma pneumonia in three sisters with sickle cell disease.Pediatr Hematol Oncol 3, no. 3 (1986): 259–65. https://doi.org/10.3109/08880018609031225.
Becton DL, Friedman HS, Kurtzberg J, Chaffee S, Falletta JM, Kinney TR. Severe Mycoplasma pneumonia in three sisters with sickle cell disease. Pediatr Hematol Oncol. 1986;3(3):259–65.
Becton, D. L., et al. “Severe Mycoplasma pneumonia in three sisters with sickle cell disease.Pediatr Hematol Oncol, vol. 3, no. 3, 1986, pp. 259–65. Pubmed, doi:10.3109/08880018609031225.
Becton DL, Friedman HS, Kurtzberg J, Chaffee S, Falletta JM, Kinney TR. Severe Mycoplasma pneumonia in three sisters with sickle cell disease. Pediatr Hematol Oncol. 1986;3(3):259–265.
Journal cover image

Published In

Pediatr Hematol Oncol

DOI

ISSN

0888-0018

Publication Date

1986

Volume

3

Issue

3

Start / End Page

259 / 265

Location

England

Related Subject Headings

  • Radiography
  • Pneumonia, Mycoplasma
  • Pleural Effusion
  • Oncology & Carcinogenesis
  • Humans
  • Female
  • Family
  • Combined Modality Therapy
  • Child
  • Anemia, Sickle Cell