A seven-month survival of a calf with an artificial heart designed for human use.
Publication
, Journal Article
Mochizuki, T; Lawson, JH; Olsen, DB; Fukumasu, H; Daitoh, N; Jarvik, R; Kessler, TR; Pons, AB; Hastings, L; Razzeca, KJ; Nielsen, SD; Kolff, WJ
Published in: Artif Organs
May 1981
A Jarvik-7 type of pneumatic artificial heart, which was specifically designed to fit the anatomy and hemodynamic requirements of human patients, was implanted in a calf in an experiment to test the hemodynamic performance of the artificial heart. The experiment lasted for 221 days, longer than any animal had ever lived without its natural heart, despite the fact that the calf increased its body weight to 171 kg. The calf showed typical signs of low cardiac output before its death, but the direct cause of death was intestinal bleeding. At autopsy, it was discovered that the low cardiac output was due to severe pannus around the left inflow valve, as diagnosed earlier by changes in the pneumatic pressure wave form.
Duke Scholars
Published In
Artif Organs
DOI
ISSN
0160-564X
Publication Date
May 1981
Volume
5
Issue
2
Start / End Page
125 / 131
Location
United States
Related Subject Headings
- Surgical Procedures, Operative
- Male
- Hemodynamics
- Heart, Artificial
- Heart Rate
- Heart Function Tests
- Heart
- Cattle
- Cardiac Output
- Biomedical Engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Mochizuki, T., Lawson, J. H., Olsen, D. B., Fukumasu, H., Daitoh, N., Jarvik, R., … Kolff, W. J. (1981). A seven-month survival of a calf with an artificial heart designed for human use. Artif Organs, 5(2), 125–131. https://doi.org/10.1111/j.1525-1594.1981.tb03974.x
Mochizuki, T., J. H. Lawson, D. B. Olsen, H. Fukumasu, N. Daitoh, R. Jarvik, T. R. Kessler, et al. “A seven-month survival of a calf with an artificial heart designed for human use.” Artif Organs 5, no. 2 (May 1981): 125–31. https://doi.org/10.1111/j.1525-1594.1981.tb03974.x.
Mochizuki T, Lawson JH, Olsen DB, Fukumasu H, Daitoh N, Jarvik R, et al. A seven-month survival of a calf with an artificial heart designed for human use. Artif Organs. 1981 May;5(2):125–31.
Mochizuki, T., et al. “A seven-month survival of a calf with an artificial heart designed for human use.” Artif Organs, vol. 5, no. 2, May 1981, pp. 125–31. Pubmed, doi:10.1111/j.1525-1594.1981.tb03974.x.
Mochizuki T, Lawson JH, Olsen DB, Fukumasu H, Daitoh N, Jarvik R, Kessler TR, Pons AB, Hastings L, Razzeca KJ, Nielsen SD, Kolff WJ. A seven-month survival of a calf with an artificial heart designed for human use. Artif Organs. 1981 May;5(2):125–131.
Published In
Artif Organs
DOI
ISSN
0160-564X
Publication Date
May 1981
Volume
5
Issue
2
Start / End Page
125 / 131
Location
United States
Related Subject Headings
- Surgical Procedures, Operative
- Male
- Hemodynamics
- Heart, Artificial
- Heart Rate
- Heart Function Tests
- Heart
- Cattle
- Cardiac Output
- Biomedical Engineering