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Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression.

Publication ,  Journal Article
Nicchitta, CV
Published in: J Clin Invest
September 2003

CD1d, a nonclassical MHC class I-like molecule, is prominently expressed on intestinal epithelial cells and is thought to function in the regulation of intestinal intraepithelial lymphocyte activity. Hsp110, an abundant heat shock protein present in essentially all mammalian tissues, has now been shown to upregulate CD1d expression in colonic tissue culture cell lines. Might this abundant chaperone serve an autocrine function in the regulation of CD1d expression?

Duke Scholars

Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

September 2003

Volume

112

Issue

5

Start / End Page

646 / 648

Location

United States

Related Subject Headings

  • Intestinal Mucosa
  • Immunology
  • Humans
  • HSP70 Heat-Shock Proteins
  • HSP110 Heat-Shock Proteins
  • Gene Expression Regulation
  • Extracellular Space
  • Antigens, CD1d
  • Antigens, CD1
  • 42 Health sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nicchitta, C. V. (2003). Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. J Clin Invest, 112(5), 646–648. https://doi.org/10.1172/JCI19641
Nicchitta, Christopher V. “Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression.J Clin Invest 112, no. 5 (September 2003): 646–48. https://doi.org/10.1172/JCI19641.
Nicchitta, Christopher V. “Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression.J Clin Invest, vol. 112, no. 5, Sept. 2003, pp. 646–48. Pubmed, doi:10.1172/JCI19641.
Nicchitta CV. Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression. J Clin Invest. 2003 Sep;112(5):646–648.

Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

September 2003

Volume

112

Issue

5

Start / End Page

646 / 648

Location

United States

Related Subject Headings

  • Intestinal Mucosa
  • Immunology
  • Humans
  • HSP70 Heat-Shock Proteins
  • HSP110 Heat-Shock Proteins
  • Gene Expression Regulation
  • Extracellular Space
  • Antigens, CD1d
  • Antigens, CD1
  • 42 Health sciences