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Seven-transmembrane-spanning receptors and heart function.

Publication ,  Journal Article
Rockman, HA; Koch, WJ; Lefkowitz, RJ
Published in: Nature
January 10, 2002

Understanding precisely how the heart can recognize and respond to many different extracellular signalling molecules, such as neurotransmitters, hormones and growth factors, will aid the identification of new therapeutic targets through which cardiovascular diseases can be combated. In recent years, we have learned more about the complex interactions that occur between the receptors and the signalling pathways of the heart and its environment. Most of these discoveries have focused on the most common type of cardiac receptor - the seven-transmembrane-spanning receptor or G-protein-coupled receptor.

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Published In

Nature

DOI

ISSN

0028-0836

Publication Date

January 10, 2002

Volume

415

Issue

6868

Start / End Page

206 / 212

Location

England

Related Subject Headings

  • beta-Adrenergic Receptor Kinases
  • Signal Transduction
  • Receptors, Muscarinic
  • Receptors, Cell Surface
  • Receptors, Adrenergic
  • Protein Conformation
  • Mice
  • Humans
  • Heart Diseases
  • Heart
 

Citation

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Rockman, H. A., Koch, W. J., & Lefkowitz, R. J. (2002). Seven-transmembrane-spanning receptors and heart function. Nature, 415(6868), 206–212. https://doi.org/10.1038/415206a
Rockman, Howard A., Walter J. Koch, and Robert J. Lefkowitz. “Seven-transmembrane-spanning receptors and heart function.Nature 415, no. 6868 (January 10, 2002): 206–12. https://doi.org/10.1038/415206a.
Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 2002 Jan 10;415(6868):206–12.
Rockman, Howard A., et al. “Seven-transmembrane-spanning receptors and heart function.Nature, vol. 415, no. 6868, Jan. 2002, pp. 206–12. Pubmed, doi:10.1038/415206a.
Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 2002 Jan 10;415(6868):206–212.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

January 10, 2002

Volume

415

Issue

6868

Start / End Page

206 / 212

Location

England

Related Subject Headings

  • beta-Adrenergic Receptor Kinases
  • Signal Transduction
  • Receptors, Muscarinic
  • Receptors, Cell Surface
  • Receptors, Adrenergic
  • Protein Conformation
  • Mice
  • Humans
  • Heart Diseases
  • Heart