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Fibrinogen content of low-volume cryoprecipitate.

Publication ,  Journal Article
Hoffman, M; Koepke, JA; Widmann, FK
Published in: Transfusion
1987

Single-donor cryoprecipitate is the most convenient and reliable source of fibrinogen. A change by the regional Red Cross Blood Service to the production of low-volume cryoprecipitate led the authors to reexamine the fibrinogen content of cryoprecipitate units. The average fibrinogen content of individual low-volume (4 ml) units (n = 23) was 101 +/- 48 mg; in the 10-unit pools (n = 9 pools), content was 89 +/- 13 mg. Both measurements were considerably lower than previously published. By contrast, the mean fibrinogen content of regular-volume (15 ml) cryoprecipitate units (n = 8) was 142 +/- 50 mg. The fibrinogen was stable for at least 4 hours after thawing, and it survived refreezing and thawing.

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Published In

Transfusion

DOI

ISSN

0041-1132

Publication Date

1987

Volume

27

Issue

4

Start / End Page

356 / 358

Location

United States

Related Subject Headings

  • Quality Control
  • Plasma
  • Humans
  • Fibrinogen
  • Factor VIII
  • Cold Temperature
  • Cardiovascular System & Hematology
  • Blood Banks
  • 3204 Immunology
  • 3202 Clinical sciences
 

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Hoffman, M., Koepke, J. A., & Widmann, F. K. (1987). Fibrinogen content of low-volume cryoprecipitate. Transfusion, 27(4), 356–358. https://doi.org/10.1046/j.1537-2995.1987.27487264748.x
Hoffman, M., J. A. Koepke, and F. K. Widmann. “Fibrinogen content of low-volume cryoprecipitate.Transfusion 27, no. 4 (1987): 356–58. https://doi.org/10.1046/j.1537-2995.1987.27487264748.x.
Hoffman M, Koepke JA, Widmann FK. Fibrinogen content of low-volume cryoprecipitate. Transfusion. 1987;27(4):356–8.
Hoffman, M., et al. “Fibrinogen content of low-volume cryoprecipitate.Transfusion, vol. 27, no. 4, 1987, pp. 356–58. Pubmed, doi:10.1046/j.1537-2995.1987.27487264748.x.
Hoffman M, Koepke JA, Widmann FK. Fibrinogen content of low-volume cryoprecipitate. Transfusion. 1987;27(4):356–358.
Journal cover image

Published In

Transfusion

DOI

ISSN

0041-1132

Publication Date

1987

Volume

27

Issue

4

Start / End Page

356 / 358

Location

United States

Related Subject Headings

  • Quality Control
  • Plasma
  • Humans
  • Fibrinogen
  • Factor VIII
  • Cold Temperature
  • Cardiovascular System & Hematology
  • Blood Banks
  • 3204 Immunology
  • 3202 Clinical sciences