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Early recurrent ischemic stroke. A case-control study.

Publication ,  Journal Article
Goldstein, LB; Perry, A
Published in: Stroke
July 1992

BACKGROUND AND PURPOSE: Data concerning potentially treatable risk factors for early recurrent stroke are limited. Therefore, we carried out a retrospective case-control study to identify factors predisposing to early reinfarction. SUMMARY OF REVIEW: We identified all patients admitted to Duke University Hospital or the Durham Veterans Administration Medical Center during 1 year having two documented ischemic strokes within 90 days (n = 12 of 273). Twelve randomly selected patients matched for age, sex, and race but having only a single stroke served as controls. There were no significant differences between the groups with respect to a variety of factors including the presence of hypertension, diabetes, a history of transient ischemic attack, a history of stroke, cerebral site of the index stroke, and subtype of the index stroke. A potential cardioembolic source was more frequently identified in the patients with early recurrent stroke (seven of the 12 case-control pairs were discordant for a potential cardioembolic source; McNemar's chi 2 test, p less than or equal to 0.02). CONCLUSIONS: Of the variables examined, the presence of a potential cardioembolic source was the single statistically significant factor associated with reinfarction within the first 90 days after ischemic stroke. The limitations and possible therapeutic implications of these results are discussed.

Duke Scholars

Published In

Stroke

DOI

ISSN

0039-2499

Publication Date

July 1992

Volume

23

Issue

7

Start / End Page

1010 / 1013

Location

United States

Related Subject Headings

  • Risk Factors
  • Retrospective Studies
  • Recurrence
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Heart Diseases
  • Female
  • Cerebrovascular Disorders
  • Case-Control Studies
 

Citation

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ICMJE
MLA
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Goldstein, L. B., & Perry, A. (1992). Early recurrent ischemic stroke. A case-control study. Stroke, 23(7), 1010–1013. https://doi.org/10.1161/01.str.23.7.1010
Goldstein, L. B., and A. Perry. “Early recurrent ischemic stroke. A case-control study.Stroke 23, no. 7 (July 1992): 1010–13. https://doi.org/10.1161/01.str.23.7.1010.
Goldstein LB, Perry A. Early recurrent ischemic stroke. A case-control study. Stroke. 1992 Jul;23(7):1010–3.
Goldstein, L. B., and A. Perry. “Early recurrent ischemic stroke. A case-control study.Stroke, vol. 23, no. 7, July 1992, pp. 1010–13. Pubmed, doi:10.1161/01.str.23.7.1010.
Goldstein LB, Perry A. Early recurrent ischemic stroke. A case-control study. Stroke. 1992 Jul;23(7):1010–1013.

Published In

Stroke

DOI

ISSN

0039-2499

Publication Date

July 1992

Volume

23

Issue

7

Start / End Page

1010 / 1013

Location

United States

Related Subject Headings

  • Risk Factors
  • Retrospective Studies
  • Recurrence
  • Neurology & Neurosurgery
  • Male
  • Humans
  • Heart Diseases
  • Female
  • Cerebrovascular Disorders
  • Case-Control Studies