Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats.
Publication
, Journal Article
Goldstein, LB; Davis, JN
Published in: Behav Neurosci
April 1990
Amphetamine treatment facilitates recovery of beam-walking in rats with unilateral sensorimotor cortex lesions. Lesion extent was studied in amphetamine- and saline-treated rats selected for rapid and slow recoveries. Lesion volume, lesion depth, and the amount of medial cortex damage were not different among the 4 groups of rats. When the data were analyzed without regard to drug treatment, both lesion depth in rostral forebrain and maximum amount of medial cortex damage negatively correlated with recovery rate. Thus, lesion extent influences the rate of recovery of beam-walking in rats but does not explain the lack of effectiveness of amphetamine in selected animals.
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Published In
Behav Neurosci
DOI
ISSN
0735-7044
Publication Date
April 1990
Volume
104
Issue
2
Start / End Page
320 / 327
Location
United States
Related Subject Headings
- Somatosensory Cortex
- Rats, Inbred Strains
- Rats
- Neural Pathways
- Nerve Regeneration
- Motor Skills
- Motor Cortex
- Male
- Injections, Intraperitoneal
- Hippocampus
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Goldstein, L. B., & Davis, J. N. (1990). Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behav Neurosci, 104(2), 320–327. https://doi.org/10.1037//0735-7044.104.2.320
Goldstein, L. B., and J. N. Davis. “Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats.” Behav Neurosci 104, no. 2 (April 1990): 320–27. https://doi.org/10.1037//0735-7044.104.2.320.
Goldstein LB, Davis JN. Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behav Neurosci. 1990 Apr;104(2):320–7.
Goldstein, L. B., and J. N. Davis. “Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats.” Behav Neurosci, vol. 104, no. 2, Apr. 1990, pp. 320–27. Pubmed, doi:10.1037//0735-7044.104.2.320.
Goldstein LB, Davis JN. Influence of lesion size and location on amphetamine-facilitated recovery of beam-walking in rats. Behav Neurosci. 1990 Apr;104(2):320–327.
Published In
Behav Neurosci
DOI
ISSN
0735-7044
Publication Date
April 1990
Volume
104
Issue
2
Start / End Page
320 / 327
Location
United States
Related Subject Headings
- Somatosensory Cortex
- Rats, Inbred Strains
- Rats
- Neural Pathways
- Nerve Regeneration
- Motor Skills
- Motor Cortex
- Male
- Injections, Intraperitoneal
- Hippocampus