Skip to main content
Journal cover image

The role of the subependymal plate in glial tumorigenesis.

Publication ,  Journal Article
Vick, NA; Lin, MJ; Bigner, DD
Published in: Acta Neuropathol
September 26, 1977

We have studied the sequential morphological events of glial tumorigenesis in neonatal dogs, using high titer subgroup C Bratislava-77 Avian Sarcoma Virus, given as 0.01 ml by intraventricular inoculation. The cells of the subependymal plate are those which seem to form the gliomas; cytoplasmic alterations are evident within 24 h after inoculation and microfoci of gliomas, contiguous with the subependymal plate of the lateral ventricles, are visible within 7 days. Independent tumors are present by the 10th post-inoculation day. These studies support the hypothesis of Globus and Kuhlenbeck, which implicates the cells of the subependymal palte in glial tumorigenesis.

Duke Scholars

Published In

Acta Neuropathol

DOI

ISSN

0001-6322

Publication Date

September 26, 1977

Volume

40

Issue

1

Start / End Page

63 / 71

Location

Germany

Related Subject Headings

  • Time Factors
  • Neurology & Neurosurgery
  • Microscopy, Electron
  • Glioma
  • Ependyma
  • Dogs
  • Cerebral Ventricles
  • Cell Transformation, Viral
  • Brain
  • Avian Sarcoma Viruses
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vick, N. A., Lin, M. J., & Bigner, D. D. (1977). The role of the subependymal plate in glial tumorigenesis. Acta Neuropathol, 40(1), 63–71. https://doi.org/10.1007/BF00688574
Vick, N. A., M. J. Lin, and D. D. Bigner. “The role of the subependymal plate in glial tumorigenesis.Acta Neuropathol 40, no. 1 (September 26, 1977): 63–71. https://doi.org/10.1007/BF00688574.
Vick NA, Lin MJ, Bigner DD. The role of the subependymal plate in glial tumorigenesis. Acta Neuropathol. 1977 Sep 26;40(1):63–71.
Vick, N. A., et al. “The role of the subependymal plate in glial tumorigenesis.Acta Neuropathol, vol. 40, no. 1, Sept. 1977, pp. 63–71. Pubmed, doi:10.1007/BF00688574.
Vick NA, Lin MJ, Bigner DD. The role of the subependymal plate in glial tumorigenesis. Acta Neuropathol. 1977 Sep 26;40(1):63–71.
Journal cover image

Published In

Acta Neuropathol

DOI

ISSN

0001-6322

Publication Date

September 26, 1977

Volume

40

Issue

1

Start / End Page

63 / 71

Location

Germany

Related Subject Headings

  • Time Factors
  • Neurology & Neurosurgery
  • Microscopy, Electron
  • Glioma
  • Ependyma
  • Dogs
  • Cerebral Ventricles
  • Cell Transformation, Viral
  • Brain
  • Avian Sarcoma Viruses