Skip to main content
Journal cover image

In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4.

Publication ,  Journal Article
Buckley, PJ; Kosturko, LD; Kozinski, AW
Published in: Proc Natl Acad Sci U S A
November 1972

An RNA-DNA copolymer was isolated from Escherichia coli infected with bacteriophage T4. The RNA and DNA are covalently linked, and in the same polynucleotide strand. The DNA of the copolymer hybridizes specifically to the left strand of phage T4 DNA. The copolymer is produced in cells infected with amber mutants of phage T4 deficient in DNA replication and is not inhibited by the addition of chloramphenicol.

Duke Scholars

Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

November 1972

Volume

69

Issue

11

Start / End Page

3165 / 3169

Location

United States

Related Subject Headings

  • Tritium
  • Thymidine
  • Ribonucleases
  • RNA, Viral
  • Phosphorus Isotopes
  • Nucleic Acid Hybridization
  • Mutation
  • Lysogeny
  • Hydrolysis
  • Escherichia coli
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Buckley, P. J., Kosturko, L. D., & Kozinski, A. W. (1972). In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4. Proc Natl Acad Sci U S A, 69(11), 3165–3169. https://doi.org/10.1073/pnas.69.11.3165
Buckley, P. J., L. D. Kosturko, and A. W. Kozinski. “In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4.Proc Natl Acad Sci U S A 69, no. 11 (November 1972): 3165–69. https://doi.org/10.1073/pnas.69.11.3165.
Buckley PJ, Kosturko LD, Kozinski AW. In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4. Proc Natl Acad Sci U S A. 1972 Nov;69(11):3165–9.
Buckley, P. J., et al. “In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4.Proc Natl Acad Sci U S A, vol. 69, no. 11, Nov. 1972, pp. 3165–69. Pubmed, doi:10.1073/pnas.69.11.3165.
Buckley PJ, Kosturko LD, Kozinski AW. In vivo production of an RNA-DNA copolymer after infection of Escherichia coli by bacteriophage T4. Proc Natl Acad Sci U S A. 1972 Nov;69(11):3165–3169.
Journal cover image

Published In

Proc Natl Acad Sci U S A

DOI

ISSN

0027-8424

Publication Date

November 1972

Volume

69

Issue

11

Start / End Page

3165 / 3169

Location

United States

Related Subject Headings

  • Tritium
  • Thymidine
  • Ribonucleases
  • RNA, Viral
  • Phosphorus Isotopes
  • Nucleic Acid Hybridization
  • Mutation
  • Lysogeny
  • Hydrolysis
  • Escherichia coli