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Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus.

Publication ,  Journal Article
Yao, HH-C; Capel, B
Published in: J Biochem
July 2005

Sex determination, the step at which differentiation of males and females is initiated in the embryo, is of central importance to the propagation of species. There is a remarkable diversity of mechanisms by which sex determination is accomplished. In general these mechanisms fall into two categories: Genetic Sex Determination (GSD), which depends on genetic differences between the sexes, and Environmental Sex Determination (ESD), which depends on extrinsic cues. In this review we will consider these two means of determining sex with particular emphasis on two species: a species that depends on GSD, Mus musculus, and a species that depends on ESD, Trachemys scripta. Because the structural organization of the adult testis and ovary is very similar across vertebrates, most biologists had expected that the pathways downstream of the sex-determining switch would be conserved. However, emerging data indicate that not only are the initial sex determining mechanisms different, but the downstream pathways and morphogenetic events leading to the development of a testis or ovary also are different.

Duke Scholars

Published In

J Biochem

DOI

ISSN

0021-924X

Publication Date

July 2005

Volume

138

Issue

1

Start / End Page

5 / 12

Location

England

Related Subject Headings

  • Turtles
  • Transcription Factors
  • Testis
  • Temperature
  • Sex Differentiation
  • Sex Determination Processes
  • Ovary
  • Organogenesis
  • Mice
  • Male
 

Citation

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Yao, H.-C., & Capel, B. (2005). Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus. J Biochem, 138(1), 5–12. https://doi.org/10.1093/jb/mvi097
Yao, Humphrey H-C, and Blanche Capel. “Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus.J Biochem 138, no. 1 (July 2005): 5–12. https://doi.org/10.1093/jb/mvi097.
Yao, Humphrey H. C., and Blanche Capel. “Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus.J Biochem, vol. 138, no. 1, July 2005, pp. 5–12. Pubmed, doi:10.1093/jb/mvi097.
Journal cover image

Published In

J Biochem

DOI

ISSN

0021-924X

Publication Date

July 2005

Volume

138

Issue

1

Start / End Page

5 / 12

Location

England

Related Subject Headings

  • Turtles
  • Transcription Factors
  • Testis
  • Temperature
  • Sex Differentiation
  • Sex Determination Processes
  • Ovary
  • Organogenesis
  • Mice
  • Male