Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome.
Publication
, Journal Article
Addison, WA; Hammond, CB; Tyrey, L; Schomberg, DW
Published in: Obstet Gynecol
March 1976
Two siblings are presented, both with classic androgen-insensitivity syndrome (AIS). Endocrine testing was carried out and then gonadectomy was performed. Studies in these patients with AIS revealed low control serum FSH. In these patients serum FSH was not significantly suppressed by intravenous estrogen nor adequately stimulated by FSH-LH-releasing hormone but rose normally after castration. The various studies are interpreted in the light of the known kinetics of pituitary gonadotorpins and their modulation by gonadal steroids. A third sibling is also presented.
Duke Scholars
Published In
Obstet Gynecol
ISSN
0029-7844
Publication Date
March 1976
Volume
47
Issue
3
Start / End Page
331 / 336
Location
United States
Related Subject Headings
- Stimulation, Chemical
- Obstetrics & Reproductive Medicine
- Male
- Luteinizing Hormone
- Kinetics
- Humans
- Gonadotropin-Releasing Hormone
- Follicle Stimulating Hormone
- Female
- Androgens
Citation
APA
Chicago
ICMJE
MLA
NLM
Addison, W. A., Hammond, C. B., Tyrey, L., & Schomberg, D. W. (1976). Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome. Obstet Gynecol, 47(3), 331–336.
Addison, W. A., C. B. Hammond, L. Tyrey, and D. W. Schomberg. “Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome.” Obstet Gynecol 47, no. 3 (March 1976): 331–36.
Addison WA, Hammond CB, Tyrey L, Schomberg DW. Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome. Obstet Gynecol. 1976 Mar;47(3):331–6.
Addison, W. A., et al. “Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome.” Obstet Gynecol, vol. 47, no. 3, Mar. 1976, pp. 331–36.
Addison WA, Hammond CB, Tyrey L, Schomberg DW. Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome. Obstet Gynecol. 1976 Mar;47(3):331–336.
Published In
Obstet Gynecol
ISSN
0029-7844
Publication Date
March 1976
Volume
47
Issue
3
Start / End Page
331 / 336
Location
United States
Related Subject Headings
- Stimulation, Chemical
- Obstetrics & Reproductive Medicine
- Male
- Luteinizing Hormone
- Kinetics
- Humans
- Gonadotropin-Releasing Hormone
- Follicle Stimulating Hormone
- Female
- Androgens