Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe.
Publication
, Journal Article
Pupkin, MJ; Schomberg, DW; Nagey, DA; Crenshaw, C
Published in: Am J Obstet Gynecol
January 15, 1975
The fetoplacental unit of the ewe is capable of increasing the biosynthesis of estrogens following the exogenous administration of DHEA to the fetus. The maximum concentrations of estrogens appeared approximately 30 minutes after the administration of DHEA. Uterine blood flow in the pregnant ewe increased approximately 90 minutes after the maximum concentrations of estrogens were noted. The administration of DHEA to the nonpregnant, ovariectomized ewe did not elicit estrogen biosynthesis or changes in uterine blood flow. Isotope experiments in the pregnant ewe demonstrated the incorporation of DHEA into urinary estradiol.
Duke Scholars
Published In
Am J Obstet Gynecol
DOI
ISSN
0002-9378
Publication Date
January 15, 1975
Volume
121
Issue
2
Start / End Page
227 / 232
Location
United States
Related Subject Headings
- Uterus
- Umbilical Arteries
- Tritium
- Time Factors
- Sheep
- Scintillation Counting
- Regional Blood Flow
- Radioimmunoassay
- Pregnancy
- Placenta
Citation
APA
Chicago
ICMJE
MLA
NLM
Pupkin, M. J., Schomberg, D. W., Nagey, D. A., & Crenshaw, C. (1975). Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. Am J Obstet Gynecol, 121(2), 227–232. https://doi.org/10.1016/0002-9378(75)90645-6
Pupkin, M. J., D. W. Schomberg, D. A. Nagey, and C. Crenshaw. “Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe.” Am J Obstet Gynecol 121, no. 2 (January 15, 1975): 227–32. https://doi.org/10.1016/0002-9378(75)90645-6.
Pupkin MJ, Schomberg DW, Nagey DA, Crenshaw C. Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. Am J Obstet Gynecol. 1975 Jan 15;121(2):227–32.
Pupkin, M. J., et al. “Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe.” Am J Obstet Gynecol, vol. 121, no. 2, Jan. 1975, pp. 227–32. Pubmed, doi:10.1016/0002-9378(75)90645-6.
Pupkin MJ, Schomberg DW, Nagey DA, Crenshaw C. Effect of exogenous dehydroepiandrosterone upon the fetoplacental biosynthesis of estrogens and its effect upon uterine blood flow in the term pregnant ewe. Am J Obstet Gynecol. 1975 Jan 15;121(2):227–232.
Published In
Am J Obstet Gynecol
DOI
ISSN
0002-9378
Publication Date
January 15, 1975
Volume
121
Issue
2
Start / End Page
227 / 232
Location
United States
Related Subject Headings
- Uterus
- Umbilical Arteries
- Tritium
- Time Factors
- Sheep
- Scintillation Counting
- Regional Blood Flow
- Radioimmunoassay
- Pregnancy
- Placenta