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A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development.

Publication ,  Journal Article
Nagey, DA; Pupkin, MJ; MacKenna, J; Schomberg, DW; Crenshaw, C
Published in: Am J Obstet Gynecol
May 15, 1976

A physiologic model of the dynamics of fetoplacental unit dehydroepiandrosterone (HDEA) to estrogen conversion is presented. A mathematical representation of this model is included. The model is used in Part II to determine the rate constant of DHEA to estrogen conversion and to successfully identify those fetuses in jeopardy from placental insufficiency within the population studied. This presentation permits critical comprehension of the model without extensive mathematical background.

Duke Scholars

Published In

Am J Obstet Gynecol

DOI

ISSN

0002-9378

Publication Date

May 15, 1976

Volume

125

Issue

2

Start / End Page

249 / 255

Location

United States

Related Subject Headings

  • Pregnancy
  • Placental Insufficiency
  • Placenta
  • Obstetrics & Reproductive Medicine
  • Models, Biological
  • Mathematics
  • Maternal-Fetal Exchange
  • Kinetics
  • Humans
  • Fetus
 

Citation

APA
Chicago
ICMJE
MLA
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Nagey, D. A., Pupkin, M. J., MacKenna, J., Schomberg, D. W., & Crenshaw, C. (1976). A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development. Am J Obstet Gynecol, 125(2), 249–255. https://doi.org/10.1016/0002-9378(76)90602-5
Nagey, D. A., M. J. Pupkin, J. MacKenna, D. W. Schomberg, and C. Crenshaw. “A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development.Am J Obstet Gynecol 125, no. 2 (May 15, 1976): 249–55. https://doi.org/10.1016/0002-9378(76)90602-5.
Nagey DA, Pupkin MJ, MacKenna J, Schomberg DW, Crenshaw C. A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development. Am J Obstet Gynecol. 1976 May 15;125(2):249–55.
Nagey, D. A., et al. “A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development.Am J Obstet Gynecol, vol. 125, no. 2, May 1976, pp. 249–55. Pubmed, doi:10.1016/0002-9378(76)90602-5.
Nagey DA, Pupkin MJ, MacKenna J, Schomberg DW, Crenshaw C. A physiologic model of the dehydroepiandrosterone to estrogen conversion system in the fetoplacental unit. I. Development. Am J Obstet Gynecol. 1976 May 15;125(2):249–255.
Journal cover image

Published In

Am J Obstet Gynecol

DOI

ISSN

0002-9378

Publication Date

May 15, 1976

Volume

125

Issue

2

Start / End Page

249 / 255

Location

United States

Related Subject Headings

  • Pregnancy
  • Placental Insufficiency
  • Placenta
  • Obstetrics & Reproductive Medicine
  • Models, Biological
  • Mathematics
  • Maternal-Fetal Exchange
  • Kinetics
  • Humans
  • Fetus