Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.
Publication
, Journal Article
Brown, HL; Klein, L; Waitzman, M
Published in: Am J Perinatol
April 1987
To study the involvement of 6 keto prostaglandin F1 alpha (6 keto PGF1 alpha) and thromboxane B2 (TxB2) in mild pregnancy-induced hypertension (PIH), we measured amniotic fluid and plasma concentration of these prostanoids by radioimmunoassay in PIH subjects and normotensive pregnant controls. The results suggest no difference in plasma or amniotic fluid 6 keto PGF1 alpha or plasma TxB2 in PIH and control subjects. The concentration of TxB2 (mean +/- SE) in amniotic fluid, however, were 189.5 +/- 27.7 for PIH and 107.4 +/- 9.7 for controls (P less than 0.05). This increase in vasoconstrictor TxB2 over vasodilator 6 keto PGF1 alpha may have implications in the hypertensive vascular response of mild PIH.
Duke Scholars
Published In
Am J Perinatol
DOI
ISSN
0735-1631
Publication Date
April 1987
Volume
4
Issue
2
Start / End Page
152 / 154
Location
United States
Related Subject Headings
- Thromboxane B2
- Pregnancy Complications, Cardiovascular
- Pregnancy
- Obstetrics & Reproductive Medicine
- Hypertension
- Humans
- Female
- Amniotic Fluid
- Adult
- 6-Ketoprostaglandin F1 alpha
Citation
APA
Chicago
ICMJE
MLA
NLM
Brown, H. L., Klein, L., & Waitzman, M. (1987). Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension. Am J Perinatol, 4(2), 152–154. https://doi.org/10.1055/s-2007-999761
Brown, H. L., L. Klein, and M. Waitzman. “Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.” Am J Perinatol 4, no. 2 (April 1987): 152–54. https://doi.org/10.1055/s-2007-999761.
Brown HL, Klein L, Waitzman M. Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension. Am J Perinatol. 1987 Apr;4(2):152–4.
Brown, H. L., et al. “Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.” Am J Perinatol, vol. 4, no. 2, Apr. 1987, pp. 152–54. Pubmed, doi:10.1055/s-2007-999761.
Brown HL, Klein L, Waitzman M. Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension. Am J Perinatol. 1987 Apr;4(2):152–154.
Published In
Am J Perinatol
DOI
ISSN
0735-1631
Publication Date
April 1987
Volume
4
Issue
2
Start / End Page
152 / 154
Location
United States
Related Subject Headings
- Thromboxane B2
- Pregnancy Complications, Cardiovascular
- Pregnancy
- Obstetrics & Reproductive Medicine
- Hypertension
- Humans
- Female
- Amniotic Fluid
- Adult
- 6-Ketoprostaglandin F1 alpha