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Multiple gamma c-dependent cytokines regulate T-cell development.

Publication ,  Journal Article
Malek, TR; Porter, BO; He, YW
Published in: Immunol Today
February 1999

Mutations in the common gamma chain (gamma c) of cytokine receptors account for human X-linked severe combined immunodeficiency disease. gamma c contributes to ligand binding and signaling as a component of five cytokine receptors: interleukin-2-receptor (IL-2R), IL-4R, IL-7R, IL-9R and IL-15R. Here, Thomas Malek and colleagues discuss the contribution of individual gamma c-dependent cytokines in both conventional and intraepithelial T-cell development.

Duke Scholars

Published In

Immunol Today

DOI

ISSN

0167-5699

Publication Date

February 1999

Volume

20

Issue

2

Start / End Page

71 / 76

Location

England

Related Subject Headings

  • X Chromosome
  • Thymus Gland
  • T-Lymphocyte Subsets
  • Severe Combined Immunodeficiency
  • Receptors, Interleukin
  • Receptors, Cytokine
  • Receptors, Antigen, T-Cell, gamma-delta
  • Models, Immunological
  • Mice, Knockout
  • Mice
 

Citation

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MLA
NLM
Malek, T. R., Porter, B. O., & He, Y. W. (1999). Multiple gamma c-dependent cytokines regulate T-cell development. Immunol Today, 20(2), 71–76. https://doi.org/10.1016/s0167-5699(98)01391-7
Malek, T. R., B. O. Porter, and Y. W. He. “Multiple gamma c-dependent cytokines regulate T-cell development.Immunol Today 20, no. 2 (February 1999): 71–76. https://doi.org/10.1016/s0167-5699(98)01391-7.
Malek TR, Porter BO, He YW. Multiple gamma c-dependent cytokines regulate T-cell development. Immunol Today. 1999 Feb;20(2):71–6.
Malek, T. R., et al. “Multiple gamma c-dependent cytokines regulate T-cell development.Immunol Today, vol. 20, no. 2, Feb. 1999, pp. 71–76. Pubmed, doi:10.1016/s0167-5699(98)01391-7.
Malek TR, Porter BO, He YW. Multiple gamma c-dependent cytokines regulate T-cell development. Immunol Today. 1999 Feb;20(2):71–76.

Published In

Immunol Today

DOI

ISSN

0167-5699

Publication Date

February 1999

Volume

20

Issue

2

Start / End Page

71 / 76

Location

England

Related Subject Headings

  • X Chromosome
  • Thymus Gland
  • T-Lymphocyte Subsets
  • Severe Combined Immunodeficiency
  • Receptors, Interleukin
  • Receptors, Cytokine
  • Receptors, Antigen, T-Cell, gamma-delta
  • Models, Immunological
  • Mice, Knockout
  • Mice