The peptidyl-prolyl isomerase Pin1.
Publication
, Journal Article
Joseph, JD; Yeh, ES; Swenson, KI; Means, AR; Winkler,
Published in: Prog Cell Cycle Res
2003
The phospho-Ser/Thr-Pro specific prolyl-isomerase Pin1 has been implicated in multiple aspects of cell cycle regulation. It has been suggested that Pin1 function is required for both normal mitotic progression and reentry into the cell cycle from quiescence. In support of this hypothesis, numerous key regulators of G1 and mitosis have been identified as Pin1 interacting proteins. However, the cellular consequence of Pin1 binding to these proteins has rarely been rigorously characterized. In this review we focus on the role of Pin1 and its binding proteins in cell cycle regulation and the potential value of Pin1 as a therapeutic target.
Duke Scholars
Published In
Prog Cell Cycle Res
ISSN
1087-2957
Publication Date
2003
Volume
5
Start / End Page
477 / 487
Location
France
Related Subject Headings
- Protein Binding
- Peptidylprolyl Isomerase
- Neoplasms
- NIMA-Interacting Peptidylprolyl Isomerase
- Mitosis
- Humans
- G1 Phase
- Cell Cycle Proteins
- Cell Cycle
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Joseph, J. D., Yeh, E. S., Swenson, K. I., Means, A. R., & Winkler, . (2003). The peptidyl-prolyl isomerase Pin1. Prog Cell Cycle Res, 5, 477–487.
Joseph, James D., Elisabeth S. Yeh, Katherine I. Swenson, Anthony R. Means, and Anthony R. Winkler. “The peptidyl-prolyl isomerase Pin1.” Prog Cell Cycle Res 5 (2003): 477–87.
Joseph JD, Yeh ES, Swenson KI, Means AR, Winkler. The peptidyl-prolyl isomerase Pin1. Prog Cell Cycle Res. 2003;5:477–87.
Joseph, James D., et al. “The peptidyl-prolyl isomerase Pin1.” Prog Cell Cycle Res, vol. 5, 2003, pp. 477–87.
Joseph JD, Yeh ES, Swenson KI, Means AR, Winkler. The peptidyl-prolyl isomerase Pin1. Prog Cell Cycle Res. 2003;5:477–487.
Published In
Prog Cell Cycle Res
ISSN
1087-2957
Publication Date
2003
Volume
5
Start / End Page
477 / 487
Location
France
Related Subject Headings
- Protein Binding
- Peptidylprolyl Isomerase
- Neoplasms
- NIMA-Interacting Peptidylprolyl Isomerase
- Mitosis
- Humans
- G1 Phase
- Cell Cycle Proteins
- Cell Cycle
- Animals