Growth regulation and transformation of ovarian epithelium.
Publication
, Journal Article
Berchuck, A; Kohler, MF; Boente, MP; Rodriguez, GC; Whitaker, RS; Bast, RC
Published in: Cancer
January 15, 1993
The discovery of peptide growth factors and cancer-causing genes (oncogenes and tumor-suppressor genes) has provided us with the exciting opportunity to begin to understand the molecular pathology of human ovarian cancer. Activation of several genes, including HER-2/neu, myc, ras, and p53 have been described in some ovarian cancers. In addition, some protooncogenes such as the epidermal growth factor receptor (erbB) and the M-CSF receptor (fms) are expressed along with the respective ligands (peptide growth factors) in some ovarian cancers. Although the studies reviewed in this paper represent a promising beginning, we remain far from a comprehensive understanding of growth regulation and transformation of human ovarian epithelium.
Duke Scholars
Published In
Cancer
DOI
ISSN
0008-543X
Publication Date
January 15, 1993
Volume
71
Issue
2 Suppl
Start / End Page
545 / 551
Location
United States
Related Subject Headings
- Ovary
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Humans
- Female
- Epithelium
- Cell Transformation, Neoplastic
- Cell Division
- 4206 Public health
- 3211 Oncology and carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Berchuck, A., Kohler, M. F., Boente, M. P., Rodriguez, G. C., Whitaker, R. S., & Bast, R. C. (1993). Growth regulation and transformation of ovarian epithelium. Cancer, 71(2 Suppl), 545–551. https://doi.org/10.1002/cncr.2820710209
Berchuck, A., M. F. Kohler, M. P. Boente, G. C. Rodriguez, R. S. Whitaker, and R. C. Bast. “Growth regulation and transformation of ovarian epithelium.” Cancer 71, no. 2 Suppl (January 15, 1993): 545–51. https://doi.org/10.1002/cncr.2820710209.
Berchuck A, Kohler MF, Boente MP, Rodriguez GC, Whitaker RS, Bast RC. Growth regulation and transformation of ovarian epithelium. Cancer. 1993 Jan 15;71(2 Suppl):545–51.
Berchuck, A., et al. “Growth regulation and transformation of ovarian epithelium.” Cancer, vol. 71, no. 2 Suppl, Jan. 1993, pp. 545–51. Pubmed, doi:10.1002/cncr.2820710209.
Berchuck A, Kohler MF, Boente MP, Rodriguez GC, Whitaker RS, Bast RC. Growth regulation and transformation of ovarian epithelium. Cancer. 1993 Jan 15;71(2 Suppl):545–551.
Published In
Cancer
DOI
ISSN
0008-543X
Publication Date
January 15, 1993
Volume
71
Issue
2 Suppl
Start / End Page
545 / 551
Location
United States
Related Subject Headings
- Ovary
- Ovarian Neoplasms
- Oncology & Carcinogenesis
- Humans
- Female
- Epithelium
- Cell Transformation, Neoplastic
- Cell Division
- 4206 Public health
- 3211 Oncology and carcinogenesis