Virulence genes of poxviruses and reoviruses.
Publication
, Journal Article
Joklik, WK; Pickup, DJ; Patel, DD; Moody, MD
Published in: Vaccine
April 1988
Identification of viral genes that specify virulence, however defined, is of critical importance for the design of viral vaccines. In particular, the targeted development not only of avirulent vaccine strains but also of viruses to be used as carriers for foreign genes depends on the inactivation or deletion of genes that harm the host. This paper illustrates approaches to identifying viral pathogenesis genes in two model systems involving cowpox virus and reovirus, respectively.
Duke Scholars
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Published In
Vaccine
DOI
ISSN
0264-410X
Publication Date
April 1988
Volume
6
Issue
2
Start / End Page
123 / 128
Location
Netherlands
Related Subject Headings
- Virulence
- Virology
- Vaccinia virus
- Reoviridae
- Molecular Sequence Data
- Mammalian orthoreovirus 3
- Genetic Variation
- DNA, Viral
- DNA Restriction Enzymes
- Cloning, Molecular
Citation
APA
Chicago
ICMJE
MLA
NLM
Joklik, W. K., Pickup, D. J., Patel, D. D., & Moody, M. D. (1988). Virulence genes of poxviruses and reoviruses. Vaccine, 6(2), 123–128. https://doi.org/10.1016/s0264-410x(88)80013-6
Joklik, W. K., D. J. Pickup, D. D. Patel, and M. D. Moody. “Virulence genes of poxviruses and reoviruses.” Vaccine 6, no. 2 (April 1988): 123–28. https://doi.org/10.1016/s0264-410x(88)80013-6.
Joklik WK, Pickup DJ, Patel DD, Moody MD. Virulence genes of poxviruses and reoviruses. Vaccine. 1988 Apr;6(2):123–8.
Joklik, W. K., et al. “Virulence genes of poxviruses and reoviruses.” Vaccine, vol. 6, no. 2, Apr. 1988, pp. 123–28. Pubmed, doi:10.1016/s0264-410x(88)80013-6.
Joklik WK, Pickup DJ, Patel DD, Moody MD. Virulence genes of poxviruses and reoviruses. Vaccine. 1988 Apr;6(2):123–128.
Published In
Vaccine
DOI
ISSN
0264-410X
Publication Date
April 1988
Volume
6
Issue
2
Start / End Page
123 / 128
Location
Netherlands
Related Subject Headings
- Virulence
- Virology
- Vaccinia virus
- Reoviridae
- Molecular Sequence Data
- Mammalian orthoreovirus 3
- Genetic Variation
- DNA, Viral
- DNA Restriction Enzymes
- Cloning, Molecular