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The prevalence of abnormal cilia in normal pediatric lungs.

Publication ,  Journal Article
Wisseman, CL; Simel, DL; Spock, A; Shelburne, JD
Published in: Arch Pathol Lab Med
October 1981

Abnormal respiratory cells have been reported in cases of chronic pediatric respiratory infection. In some cases, there is a specific defect of most cilia, but in others there is a variety of derangements of the architecture of only a fraction of the cilia. Histologically normal lungs from two children without known respiratory disease were examined and found to contain many abnormal cilia of the polymorphic type, which accounted for 3% to 5% of all cilia. Abnormalities included (1) excess cytoplasmic matrix, (2) additions, deletions, or aberrant arrangements of the 9 + 2 tubular pattern, (3) multiple partial or complete cilia within one membrane, and (4) occasional marked disorganization of all cilia in a cell. Polymorphic ciliary abnormalities may be common in healthy children, and should be cautiously interpreted as a cause of chronic respiratory infection.

Duke Scholars

Published In

Arch Pathol Lab Med

ISSN

0003-9985

Publication Date

October 1981

Volume

105

Issue

10

Start / End Page

552 / 555

Location

United States

Related Subject Headings

  • Pathology
  • Microtubules
  • Male
  • Lung
  • Humans
  • Female
  • Cytoplasm
  • Cilia
  • Child, Preschool
  • Child
 

Citation

APA
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ICMJE
MLA
NLM
Wisseman, C. L., Simel, D. L., Spock, A., & Shelburne, J. D. (1981). The prevalence of abnormal cilia in normal pediatric lungs. Arch Pathol Lab Med, 105(10), 552–555.
Wisseman, C. L., D. L. Simel, A. Spock, and J. D. Shelburne. “The prevalence of abnormal cilia in normal pediatric lungs.Arch Pathol Lab Med 105, no. 10 (October 1981): 552–55.
Wisseman CL, Simel DL, Spock A, Shelburne JD. The prevalence of abnormal cilia in normal pediatric lungs. Arch Pathol Lab Med. 1981 Oct;105(10):552–5.
Wisseman, C. L., et al. “The prevalence of abnormal cilia in normal pediatric lungs.Arch Pathol Lab Med, vol. 105, no. 10, Oct. 1981, pp. 552–55.
Wisseman CL, Simel DL, Spock A, Shelburne JD. The prevalence of abnormal cilia in normal pediatric lungs. Arch Pathol Lab Med. 1981 Oct;105(10):552–555.

Published In

Arch Pathol Lab Med

ISSN

0003-9985

Publication Date

October 1981

Volume

105

Issue

10

Start / End Page

552 / 555

Location

United States

Related Subject Headings

  • Pathology
  • Microtubules
  • Male
  • Lung
  • Humans
  • Female
  • Cytoplasm
  • Cilia
  • Child, Preschool
  • Child