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Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex.

Publication ,  Journal Article
Huettel, SA; Mack, PB; McCarthy, G
Published in: Nature neuroscience
May 2002

We demonstrate that regions within human prefrontal cortex develop moment-to-moment models for patterns of events occurring in the sensory environment. Subjects viewed a random binary sequence of images, each presented singly and each requiring a different button press response. Patterns occurred by chance within the presented series of images. Using functional magnetic resonance imaging (fMRI), we identified activity evoked by viewing a stimulus that interrupted a pattern. Prefrontal activation was evoked by violations of both repeating and alternating patterns, and the amplitude of this activation increased with increasing pattern length. Violations of repeating patterns, but not of alternating patterns, activated the basal ganglia.

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Published In

Nature neuroscience

DOI

EISSN

1546-1726

ISSN

1097-6256

Publication Date

May 2002

Volume

5

Issue

5

Start / End Page

485 / 490

Related Subject Headings

  • Reaction Time
  • Prefrontal Cortex
  • Photic Stimulation
  • Pattern Recognition, Visual
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Brain Mapping
 

Citation

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Huettel, S. A., Mack, P. B., & McCarthy, G. (2002). Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex. Nature Neuroscience, 5(5), 485–490. https://doi.org/10.1038/nn841
Huettel, Scott A., Peter B. Mack, and Gregory McCarthy. “Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex.Nature Neuroscience 5, no. 5 (May 2002): 485–90. https://doi.org/10.1038/nn841.
Huettel SA, Mack PB, McCarthy G. Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex. Nature neuroscience. 2002 May;5(5):485–90.
Huettel, Scott A., et al. “Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex.Nature Neuroscience, vol. 5, no. 5, May 2002, pp. 485–90. Epmc, doi:10.1038/nn841.
Huettel SA, Mack PB, McCarthy G. Perceiving patterns in random series: dynamic processing of sequence in prefrontal cortex. Nature neuroscience. 2002 May;5(5):485–490.

Published In

Nature neuroscience

DOI

EISSN

1546-1726

ISSN

1097-6256

Publication Date

May 2002

Volume

5

Issue

5

Start / End Page

485 / 490

Related Subject Headings

  • Reaction Time
  • Prefrontal Cortex
  • Photic Stimulation
  • Pattern Recognition, Visual
  • Neurology & Neurosurgery
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
  • Brain Mapping