Finding the site of origin and velocity of propagation in a short one-dimensional strand from two extracellular waveforms
A method is evaluated for determining the sequence of excitation of cardiac muscles from only two known extracellular waveforms. The approach takes advantage of the entire time course of the observed waveforms, not just their intrinsic deflections. The most simple geometry, a strand in one dimension, is assumed, and a number of simplifying assumptions are used. Notable results of the study include correctly differentiating among different sequences of excitation having identical time differences between the intrinsic deflections of the two known extracellular waveforms. An implication of the results is that excitation sequences in more realistic structures might be found with a much simpler measurement protocol if more information in the extracellular waveshape were to be used
