Variability of the planarity of the human aortic bifurcation

The susceptibility of vascular branches to atherosclerosis is believed to be due in part to the unusual fluid dynamic environments that the vessel wall experiences in these regions. As vascular geometry is a primary determinant of the local haemodynamic environment, it is of interest to quantitate the geometric features of vascular branches and their variability. The present research focusses on branch planarity, using axial magnetic resonance images of the aortic bifurcations of 20 healthy subjects. The in vivo images were processed to obtain vector representations of the vessel axes at the bifurcation, from which the planarity of the bifurcation was derived using a novel robust definition. Three-dimensional reconstructions of the bifurcations were rendered using computer graphics techniques to demonstrate the variability of the planarity of this region of the vasculature; this variability might be related to variable predispositions to atherosclerosis at the aortic bifurcation.

Duke Scholars

Author Morton Friedman Biomedical Engineering