Skip to main content

A fiber optic antibody-based biosensor with time-resolved detection

Publication ,  Journal Article
Vo Dinh, T; Nolan, T; Cheng, YF; Alarie, JP; Sepaniak, MJ
Published in: Proc. SPIE - Int. Soc. Opt. Eng. (USA)
1990

A phase-resolved fiber optic antibody-based biosensor is described, which combines the biochemical specificity of antigen-antibody reaction, the high sensitivity of laser excitation, the versatility of fiber optic sensors, and the selectivity of phase-resolved detection. The device can differentiate benzo(a)pyrene and benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene. The limit of detection of benzo(a)pyrene tetrol is in the attomole range (10-18 moles)

Duke Scholars

Published In

Proc. SPIE - Int. Soc. Opt. Eng. (USA)

Publication Date

1990

Volume

1172

Start / End Page

266 / 272

Location

Boston, MA, USA

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vo Dinh, T., Nolan, T., Cheng, Y. F., Alarie, J. P., & Sepaniak, M. J. (1990). A fiber optic antibody-based biosensor with time-resolved detection. Proc. SPIE - Int. Soc. Opt. Eng. (USA), 1172, 266–272.
Vo Dinh, T., T. Nolan, Y. F. Cheng, J. P. Alarie, and M. J. Sepaniak. “A fiber optic antibody-based biosensor with time-resolved detection.” Proc. SPIE - Int. Soc. Opt. Eng. (USA) 1172 (1990): 266–72.
Vo Dinh T, Nolan T, Cheng YF, Alarie JP, Sepaniak MJ. A fiber optic antibody-based biosensor with time-resolved detection. Proc SPIE - Int Soc Opt Eng (USA). 1990;1172:266–72.
Vo Dinh, T., et al. “A fiber optic antibody-based biosensor with time-resolved detection.” Proc. SPIE - Int. Soc. Opt. Eng. (USA), vol. 1172, 1990, pp. 266–72.
Vo Dinh T, Nolan T, Cheng YF, Alarie JP, Sepaniak MJ. A fiber optic antibody-based biosensor with time-resolved detection. Proc SPIE - Int Soc Opt Eng (USA). 1990;1172:266–272.

Published In

Proc. SPIE - Int. Soc. Opt. Eng. (USA)

Publication Date

1990

Volume

1172

Start / End Page

266 / 272

Location

Boston, MA, USA

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering