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Multi-functional biochip for medical diagnostics and pathogen detection

Publication ,  Journal Article
Vo-Dinh, T; Griffin, G; Stokes, DL; Wintenberg, A
Published in: Sensors and Actuators, B: Chemical
April 20, 2003

We describe a multi-functional biochip (MFB), which uses two different types of bioreceptors, including nucleic acid and antibody probes, on a single platform. The multi-functional capability of the MFB device for biomedical diagnostics is illustrated by measurements of DNA probes specific to gene fragments of Bacillus anthracis and antibody probes targeted to Escherichia coli. Calibration curves for monitoring pathogenic species using antibody probes against E. coli and DNA probes for B. anthracis illustrate the capability of the device for medical diagnostics and for quantitative detection of pathogenic agents. © 2003 Published by Elsevier Science B.V.

Duke Scholars

Published In

Sensors and Actuators, B: Chemical

DOI

ISSN

0925-4005

Publication Date

April 20, 2003

Volume

90

Issue

1-3

Start / End Page

104 / 111

Related Subject Headings

  • Analytical Chemistry
  • 4016 Materials engineering
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 0912 Materials Engineering
  • 0301 Analytical Chemistry
  • 0205 Optical Physics
 

Citation

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Chicago
ICMJE
MLA
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Vo-Dinh, T., Griffin, G., Stokes, D. L., & Wintenberg, A. (2003). Multi-functional biochip for medical diagnostics and pathogen detection. Sensors and Actuators, B: Chemical, 90(1–3), 104–111. https://doi.org/10.1016/S0925-4005(03)00048-0
Vo-Dinh, T., G. Griffin, D. L. Stokes, and A. Wintenberg. “Multi-functional biochip for medical diagnostics and pathogen detection.” Sensors and Actuators, B: Chemical 90, no. 1–3 (April 20, 2003): 104–11. https://doi.org/10.1016/S0925-4005(03)00048-0.
Vo-Dinh T, Griffin G, Stokes DL, Wintenberg A. Multi-functional biochip for medical diagnostics and pathogen detection. Sensors and Actuators, B: Chemical. 2003 Apr 20;90(1–3):104–11.
Vo-Dinh, T., et al. “Multi-functional biochip for medical diagnostics and pathogen detection.” Sensors and Actuators, B: Chemical, vol. 90, no. 1–3, Apr. 2003, pp. 104–11. Scopus, doi:10.1016/S0925-4005(03)00048-0.
Vo-Dinh T, Griffin G, Stokes DL, Wintenberg A. Multi-functional biochip for medical diagnostics and pathogen detection. Sensors and Actuators, B: Chemical. 2003 Apr 20;90(1–3):104–111.
Journal cover image

Published In

Sensors and Actuators, B: Chemical

DOI

ISSN

0925-4005

Publication Date

April 20, 2003

Volume

90

Issue

1-3

Start / End Page

104 / 111

Related Subject Headings

  • Analytical Chemistry
  • 4016 Materials engineering
  • 4004 Chemical engineering
  • 3401 Analytical chemistry
  • 0912 Materials Engineering
  • 0301 Analytical Chemistry
  • 0205 Optical Physics