Skip to main content

Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes

Publication ,  Journal Article
Tenney, CR; Tornai, MP; Smith, MF; Turkington, TG; Jaszczak, RJ
Published in: IEEE Trans. Nucl. Sci. (USA)
2001

Depleted uranium (DU) pinhole collimators are evaluated for small-volume SPECT imaging of 511-keV gammas, with a view toward small-animal imaging. Tungsten (W) pinholes are examined for comparison. Line source measurements show planar full-width at half-maximum (FWHM) as low as 6.5 mm for a 1-mm DU pinhole, with SPECT system FWHM of 5.0 mm at 43-mm ROR and 6.7 mm at 69-mm ROR. Planar FWHM is smaller for DU than for W pinholes but is insensitive to aperture size for pinholes of 1-3 mm diameter at this energy for the collimators studied. These trends indicate penetration at pinhole edges, as confirmed by LSF shape and full-width at tenth-maximum trends. In SPECT scans of rod phantoms at 71-mm ROR, DU pinholes were only barely able to resolve cold rods as large as 4.7 mm (center-to-center spacing=2×diameter). For both F-18 alone and F-18 imaged along with Tc-99m, 3.9-mm hot rods were resolved. Tc-99m scans resolved 2.3- mm rods with F-18 present and 1.5-mm rods without F-18. DU pinhole SPECT at 511 keV does not currently match the spatial resolution of high-resolution positron emission tomography (PET) but is open to improvement and, unlike PET, is capable of simultaneous multiple-isotope acquisitions

Duke Scholars

Published In

IEEE Trans. Nucl. Sci. (USA)

DOI

Publication Date

2001

Volume

48

Issue

4

Start / End Page

1483 / 1489

Location

Lyon, France

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tenney, C. R., Tornai, M. P., Smith, M. F., Turkington, T. G., & Jaszczak, R. J. (2001). Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes. IEEE Trans. Nucl. Sci. (USA), 48(4), 1483–1489. https://doi.org/10.1109/23.958384
Tenney, C. R., M. P. Tornai, M. F. Smith, T. G. Turkington, and R. J. Jaszczak. “Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes.” IEEE Trans. Nucl. Sci. (USA) 48, no. 4 (2001): 1483–89. https://doi.org/10.1109/23.958384.
Tenney CR, Tornai MP, Smith MF, Turkington TG, Jaszczak RJ. Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes. IEEE Trans Nucl Sci (USA). 2001;48(4):1483–9.
Tenney, C. R., et al. “Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes.” IEEE Trans. Nucl. Sci. (USA), vol. 48, no. 4, 2001, pp. 1483–89. Manual, doi:10.1109/23.958384.
Tenney CR, Tornai MP, Smith MF, Turkington TG, Jaszczak RJ. Uranium pinhole collimators for 511-keV photon SPECT imaging of small volumes. IEEE Trans Nucl Sci (USA). 2001;48(4):1483–1489.

Published In

IEEE Trans. Nucl. Sci. (USA)

DOI

Publication Date

2001

Volume

48

Issue

4

Start / End Page

1483 / 1489

Location

Lyon, France

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics