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Quantitative SPECT Imaging with Indium-1111

Publication ,  Journal Article
Gilland, DR; Jaszczak, RJ; Turkington, TG; Greer, KL; Coleman, RE
Published in: IEEE Transactions on Nuclear Science
January 1, 1991
Published version (DOI)

The potential of SPECT to quantify the distribution of indium-111 was investigated in an experimental phantom study. Non-uniform attenuation compensation using acquired transmission data was compared to uniform compensation based on reconstructed quantitative accuracy and noise. The reconstructed transmission data provided the attenuation map for the non-uniform compensation. Results showed that nonuniform attenuation compensation improved image quality, quantitative accuracy, and noise compared to uniform compensation. Noise increased with a decrease in counts in the non-uniform attenuation map but remained substantially below the uniform compensation level. The noise effect was observed with both Chang and ML-EM reconstruction methods. Independent reconstruction of the 172 and 247 keV emission data was compared to the reconstruction of the combined 172 and 247 keV projection data. Improved quantitative accuracy and image noise resulted when both In-111 emission energies were used. However, independent reconstruction of the two energies did not substantially improve accuracy or noise compared with the reconstruction of the combined data. © 1991 IEEE

Duke Scholars

Ronald J. Jaszczak
Author Ronald J. Jaszczak Radiology
Timothy Garvey Turkington
Author Timothy Garvey Turkington Radiology

Published In

IEEE Transactions on Nuclear Science

DOI

10.1109/23.289386

EISSN

1558-1578

ISSN

0018-9499

Publication Date

January 1, 1991

Volume

38

Issue

2

Start / End Page

761 / 766

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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ICMJE
MLA
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Gilland, D. R., Jaszczak, R. J., Turkington, T. G., Greer, K. L., & Coleman, R. E. (1991). Quantitative SPECT Imaging with Indium-1111. IEEE Transactions on Nuclear Science, 38(2), 761–766. https://doi.org/10.1109/23.289386
Gilland, D. R., R. J. Jaszczak, T. G. Turkington, K. L. Greer, and R. E. Coleman. “Quantitative SPECT Imaging with Indium-1111.” IEEE Transactions on Nuclear Science 38, no. 2 (January 1, 1991): 761–66. https://doi.org/10.1109/23.289386.
Gilland DR, Jaszczak RJ, Turkington TG, Greer KL, Coleman RE. Quantitative SPECT Imaging with Indium-1111. IEEE Transactions on Nuclear Science. 1991 Jan 1;38(2):761–6.
Gilland, D. R., et al. “Quantitative SPECT Imaging with Indium-1111.” IEEE Transactions on Nuclear Science, vol. 38, no. 2, Jan. 1991, pp. 761–66. Scopus, doi:10.1109/23.289386.
Gilland DR, Jaszczak RJ, Turkington TG, Greer KL, Coleman RE. Quantitative SPECT Imaging with Indium-1111. IEEE Transactions on Nuclear Science. 1991 Jan 1;38(2):761–766.

Published In

IEEE Transactions on Nuclear Science

DOI

10.1109/23.289386

EISSN

1558-1578

ISSN

0018-9499

Publication Date

January 1, 1991

Volume

38

Issue

2

Start / End Page

761 / 766

Related Subject Headings

  • Nuclear & Particles Physics
  • 5106 Nuclear and plasma physics
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics