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Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin.

Publication ,  Journal Article
Kuller, JA; Sellati, LE; Chescheir, NC; Helwick, JJ; Lincoln-Boyea, B; Boor-Smith, C; McCoy, MC; Katz, VL
Published in: Am J Perinatol
March 1995

We evaluated the pregnancy outcome of all patients with elevations of both maternal serum alpha-fetoprotein and human chorionic gonadotropin since institution of combined serum screening at our program. After analysis of 34,404 samples, 99 patients were found to have significant elevations of both maternal serum alpha-fetoprotein and human chorionic gonadotropin. The ultrasound findings, amniocentesis results, and pregnancy outcomes were determined in each case. Sixty-six patients with singleton gestations met entry criteria. Pregnancy outcome information is available for 63 of these patients, 60% of whom had at least one complication. Thirty-three patients with multiple gestations met inclusion criteria. Pregnancy outcome information is available for 31 of these, 81% of whom had at least one complication. These patients had a high incidence of pregnancy related complications. This group would appear to be at higher risk than women with elevation of either maternal serum alpha-fetoprotein or human chorionic gonadotropin alone.

Duke Scholars

Published In

Am J Perinatol

DOI

ISSN

0735-1631

Publication Date

March 1995

Volume

12

Issue

2

Start / End Page

93 / 97

Location

United States

Related Subject Headings

  • alpha-Fetoproteins
  • Ultrasonography, Prenatal
  • Pregnancy, Multiple
  • Pregnancy Outcome
  • Pregnancy Complications
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Humans
  • Female
  • Chorionic Gonadotropin
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kuller, J. A., Sellati, L. E., Chescheir, N. C., Helwick, J. J., Lincoln-Boyea, B., Boor-Smith, C., … Katz, V. L. (1995). Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin. Am J Perinatol, 12(2), 93–97. https://doi.org/10.1055/s-2007-994413
Kuller, J. A., L. E. Sellati, N. C. Chescheir, J. J. Helwick, B. Lincoln-Boyea, C. Boor-Smith, M. C. McCoy, and V. L. Katz. “Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin.Am J Perinatol 12, no. 2 (March 1995): 93–97. https://doi.org/10.1055/s-2007-994413.
Kuller JA, Sellati LE, Chescheir NC, Helwick JJ, Lincoln-Boyea B, Boor-Smith C, et al. Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin. Am J Perinatol. 1995 Mar;12(2):93–7.
Kuller, J. A., et al. “Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin.Am J Perinatol, vol. 12, no. 2, Mar. 1995, pp. 93–97. Pubmed, doi:10.1055/s-2007-994413.
Kuller JA, Sellati LE, Chescheir NC, Helwick JJ, Lincoln-Boyea B, Boor-Smith C, McCoy MC, Katz VL. Outcome of pregnancies with elevation of both maternal serum alpha-fetoprotein and human chorionic gonadotropin. Am J Perinatol. 1995 Mar;12(2):93–97.
Journal cover image

Published In

Am J Perinatol

DOI

ISSN

0735-1631

Publication Date

March 1995

Volume

12

Issue

2

Start / End Page

93 / 97

Location

United States

Related Subject Headings

  • alpha-Fetoproteins
  • Ultrasonography, Prenatal
  • Pregnancy, Multiple
  • Pregnancy Outcome
  • Pregnancy Complications
  • Pregnancy
  • Obstetrics & Reproductive Medicine
  • Humans
  • Female
  • Chorionic Gonadotropin