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Gene-environment interactions in psychiatry: joining forces with neuroscience.

Publication ,  Journal Article
Caspi, A; Moffitt, TE
Published in: Nature reviews. Neuroscience
July 2006

Gene-environment interaction research in psychiatry is new, and is a natural ally of neuroscience. Mental disorders have known environmental causes, but there is heterogeneity in the response to each causal factor, which gene-environment findings attribute to genetic differences at the DNA sequence level. Such findings come from epidemiology, an ideal branch of science for showing that a gene-environment interactions exist in nature and affect a significant fraction of disease cases. The complementary discipline of epidemiology, experimental neuroscience, fuels gene-environment hypotheses and investigates underlying neural mechanisms. This article discusses opportunities and challenges in the collaboration between psychiatry, epidemiology and neuroscience in studying gene-environment interactions.

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Published In

Nature reviews. Neuroscience

DOI

EISSN

1471-0048

ISSN

1471-003X

Publication Date

July 2006

Volume

7

Issue

7

Start / End Page

583 / 590

Related Subject Headings

  • Psychiatry
  • Neurosciences
  • Neurology & Neurosurgery
  • Mental Disorders
  • Humans
  • Genetic Predisposition to Disease
  • Environment
  • Animals
  • 5202 Biological psychology
  • 3209 Neurosciences
 

Citation

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Caspi, A., & Moffitt, T. E. (2006). Gene-environment interactions in psychiatry: joining forces with neuroscience. Nature Reviews. Neuroscience, 7(7), 583–590. https://doi.org/10.1038/nrn1925
Caspi, Avshalom, and Terrie E. Moffitt. “Gene-environment interactions in psychiatry: joining forces with neuroscience.Nature Reviews. Neuroscience 7, no. 7 (July 2006): 583–90. https://doi.org/10.1038/nrn1925.
Caspi A, Moffitt TE. Gene-environment interactions in psychiatry: joining forces with neuroscience. Nature reviews Neuroscience. 2006 Jul;7(7):583–90.
Caspi, Avshalom, and Terrie E. Moffitt. “Gene-environment interactions in psychiatry: joining forces with neuroscience.Nature Reviews. Neuroscience, vol. 7, no. 7, July 2006, pp. 583–90. Epmc, doi:10.1038/nrn1925.
Caspi A, Moffitt TE. Gene-environment interactions in psychiatry: joining forces with neuroscience. Nature reviews Neuroscience. 2006 Jul;7(7):583–590.

Published In

Nature reviews. Neuroscience

DOI

EISSN

1471-0048

ISSN

1471-003X

Publication Date

July 2006

Volume

7

Issue

7

Start / End Page

583 / 590

Related Subject Headings

  • Psychiatry
  • Neurosciences
  • Neurology & Neurosurgery
  • Mental Disorders
  • Humans
  • Genetic Predisposition to Disease
  • Environment
  • Animals
  • 5202 Biological psychology
  • 3209 Neurosciences