Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.
Publication
, Journal Article
Brenner, MB; McLean, J; Scheft, H; Riberdy, J; Ang, SL; Seidman, JG; Devlin, P; Krangel, MS
Published in: Nature
February 19, 1987
The T-cell receptor (TCR) gamma polypeptide is expressed associated with CD3 (T3) on the surface of normal human peripheral blood lymphocytes. These cells function as non-MHC-restricted cytotoxic T lymphocytes (CTL)and thus may play an important role in host immune defence. The TCR gamma polypeptide occurs as a dimer in at least two molecular forms based on the absence or presence of disulphide linkage. These forms use TCR gamma polypeptides with strikingly different peptide backbone sizes.
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Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 19, 1987
Volume
325
Issue
6106
Start / End Page
689 / 694
Location
England
Related Subject Headings
- T-Lymphocytes, Cytotoxic
- Receptors, Antigen, T-Cell
- Nucleic Acid Hybridization
- Macromolecular Substances
- Immunosorbent Techniques
- Humans
- General Science & Technology
- Gene Expression Regulation
- Electrophoresis, Polyacrylamide Gel
- Disulfides
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Brenner, M. B., McLean, J., Scheft, H., Riberdy, J., Ang, S. L., Seidman, J. G., … Krangel, M. S. (1987). Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. Nature, 325(6106), 689–694. https://doi.org/10.1038/325689a0
Brenner, M. B., J. McLean, H. Scheft, J. Riberdy, S. L. Ang, J. G. Seidman, P. Devlin, and M. S. Krangel. “Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.” Nature 325, no. 6106 (February 19, 1987): 689–94. https://doi.org/10.1038/325689a0.
Brenner MB, McLean J, Scheft H, Riberdy J, Ang SL, Seidman JG, et al. Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. Nature. 1987 Feb 19;325(6106):689–94.
Brenner, M. B., et al. “Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes.” Nature, vol. 325, no. 6106, Feb. 1987, pp. 689–94. Pubmed, doi:10.1038/325689a0.
Brenner MB, McLean J, Scheft H, Riberdy J, Ang SL, Seidman JG, Devlin P, Krangel MS. Two forms of the T-cell receptor gamma protein found on peripheral blood cytotoxic T lymphocytes. Nature. 1987 Feb 19;325(6106):689–694.
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 19, 1987
Volume
325
Issue
6106
Start / End Page
689 / 694
Location
England
Related Subject Headings
- T-Lymphocytes, Cytotoxic
- Receptors, Antigen, T-Cell
- Nucleic Acid Hybridization
- Macromolecular Substances
- Immunosorbent Techniques
- Humans
- General Science & Technology
- Gene Expression Regulation
- Electrophoresis, Polyacrylamide Gel
- Disulfides