Transcriptional regulation of the human T cell receptor delta gene.
Publication
, Journal Article
Redondo, JM; Hernandez-Munain, C; Krangel, MS
Published in: Immunobiology
July 1995
T cell receptor delta gene expression is regulated by a T cell-specific transcriptional enhancer located within the J delta 3-C delta intron. An essential element of the enhancer was localized to a small 30 bp segment denoted delta E3. Two specific factors, CBF/PEBP2 and c-Myb, bind to adjacent sites within delta E3 and cooperate functionally to mediate transcriptional activation. These factors are likely to play essential roles in the developmental activation of the TCR delta gene in vivo.
Duke Scholars
Published In
Immunobiology
DOI
ISSN
0171-2985
Publication Date
July 1995
Volume
193
Issue
2-4
Start / End Page
288 / 292
Location
Netherlands
Related Subject Headings
- Transcription, Genetic
- Receptors, Antigen, T-Cell, gamma-delta
- Immunology
- Humans
- Gene Expression Regulation
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 30 Agricultural, veterinary and food sciences
- 11 Medical and Health Sciences
- 07 Agricultural and Veterinary Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Redondo, J. M., Hernandez-Munain, C., & Krangel, M. S. (1995). Transcriptional regulation of the human T cell receptor delta gene. Immunobiology, 193(2–4), 288–292. https://doi.org/10.1016/s0171-2985(11)80557-7
Redondo, J. M., C. Hernandez-Munain, and M. S. Krangel. “Transcriptional regulation of the human T cell receptor delta gene.” Immunobiology 193, no. 2–4 (July 1995): 288–92. https://doi.org/10.1016/s0171-2985(11)80557-7.
Redondo JM, Hernandez-Munain C, Krangel MS. Transcriptional regulation of the human T cell receptor delta gene. Immunobiology. 1995 Jul;193(2–4):288–92.
Redondo, J. M., et al. “Transcriptional regulation of the human T cell receptor delta gene.” Immunobiology, vol. 193, no. 2–4, July 1995, pp. 288–92. Pubmed, doi:10.1016/s0171-2985(11)80557-7.
Redondo JM, Hernandez-Munain C, Krangel MS. Transcriptional regulation of the human T cell receptor delta gene. Immunobiology. 1995 Jul;193(2–4):288–292.
Published In
Immunobiology
DOI
ISSN
0171-2985
Publication Date
July 1995
Volume
193
Issue
2-4
Start / End Page
288 / 292
Location
Netherlands
Related Subject Headings
- Transcription, Genetic
- Receptors, Antigen, T-Cell, gamma-delta
- Immunology
- Humans
- Gene Expression Regulation
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 30 Agricultural, veterinary and food sciences
- 11 Medical and Health Sciences
- 07 Agricultural and Veterinary Sciences