Protein kinase C isoenzymes: regulation and function.
Publication
, Journal Article
Blobe, GC; Stribling, S; Obeid, LM; Hannun, YA
Published in: Cancer Surv
1996
PKC is composed of an ever growing family of lipid dependent serine/threonine protein kinases. Collectively, these isoenzymes are known to mediate critical roles in signal transduction, tumour promotion and cell regulation. PKCs appear to function as switches in acute signal transduction paradigms as well as rheostats in long term cell regulation with multiple mechanisms operating in the regulation of these functions. Although these roles of PKC are well established, little is known about the regulation and roles of individual isoenzymes of PKC in vitro or in vivo.
Duke Scholars
Published In
Cancer Surv
ISSN
0261-2429
Publication Date
1996
Volume
27
Start / End Page
213 / 248
Location
United States
Related Subject Headings
- Signal Transduction
- Protein Kinase C
- Oncology & Carcinogenesis
- Isoenzymes
- Humans
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Blobe, G. C., Stribling, S., Obeid, L. M., & Hannun, Y. A. (1996). Protein kinase C isoenzymes: regulation and function. Cancer Surv, 27, 213–248.
Blobe, G. C., S. Stribling, L. M. Obeid, and Y. A. Hannun. “Protein kinase C isoenzymes: regulation and function.” Cancer Surv 27 (1996): 213–48.
Blobe GC, Stribling S, Obeid LM, Hannun YA. Protein kinase C isoenzymes: regulation and function. Cancer Surv. 1996;27:213–48.
Blobe, G. C., et al. “Protein kinase C isoenzymes: regulation and function.” Cancer Surv, vol. 27, 1996, pp. 213–48.
Blobe GC, Stribling S, Obeid LM, Hannun YA. Protein kinase C isoenzymes: regulation and function. Cancer Surv. 1996;27:213–248.
Published In
Cancer Surv
ISSN
0261-2429
Publication Date
1996
Volume
27
Start / End Page
213 / 248
Location
United States
Related Subject Headings
- Signal Transduction
- Protein Kinase C
- Oncology & Carcinogenesis
- Isoenzymes
- Humans
- Animals