Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain.
Publication
, Journal Article
Schwartz, RD; Wess, MJ; Labarca, R; Skolnick, P; Paul, SM
Published in: Brain Res
May 12, 1987
The effect of acute swim stress on the functional activity of the gamma-aminobutyric acid (GABA) receptor/chloride ion channel was studied using an assay to measure 36chloride (36Cl-) uptake into rat brain synaptoneurosomes. Muscimol-stimulated 36Cl- uptake in cerebral cortex, hippocampus, but not cerebellum, was enhanced (increased potency and efficacy) in rats subjected to 10 min of swimming, compared to non-stressed, control rats. The effect of swim stress on the activity of the GABA receptor/Cl ion channel was prevented by adrenalectomy.
Duke Scholars
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
May 12, 1987
Volume
411
Issue
1
Start / End Page
151 / 155
Location
Netherlands
Related Subject Headings
- Synaptosomes
- Swimming
- Stress, Physiological
- Receptors, GABA-A
- Rats, Inbred Strains
- Rats
- Neurology & Neurosurgery
- Muscimol
- Male
- Ion Channels
Citation
APA
Chicago
ICMJE
MLA
NLM
Schwartz, R. D., Wess, M. J., Labarca, R., Skolnick, P., & Paul, S. M. (1987). Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. Brain Res, 411(1), 151–155. https://doi.org/10.1016/0006-8993(87)90692-5
Schwartz, R. D., M. J. Wess, R. Labarca, P. Skolnick, and S. M. Paul. “Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain.” Brain Res 411, no. 1 (May 12, 1987): 151–55. https://doi.org/10.1016/0006-8993(87)90692-5.
Schwartz RD, Wess MJ, Labarca R, Skolnick P, Paul SM. Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. Brain Res. 1987 May 12;411(1):151–5.
Schwartz, R. D., et al. “Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain.” Brain Res, vol. 411, no. 1, May 1987, pp. 151–55. Pubmed, doi:10.1016/0006-8993(87)90692-5.
Schwartz RD, Wess MJ, Labarca R, Skolnick P, Paul SM. Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain. Brain Res. 1987 May 12;411(1):151–155.
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
May 12, 1987
Volume
411
Issue
1
Start / End Page
151 / 155
Location
Netherlands
Related Subject Headings
- Synaptosomes
- Swimming
- Stress, Physiological
- Receptors, GABA-A
- Rats, Inbred Strains
- Rats
- Neurology & Neurosurgery
- Muscimol
- Male
- Ion Channels