Protein serine/threonine phosphatases: life, death, and sleeping.
Publication
, Journal Article
Gallego, M; Virshup, DM
Published in: Curr Opin Cell Biol
April 2005
Protein serine/threonine phosphatases control key biological pathways including early embryonic development, cell proliferation, cell death, circadian rhythm and cancer. Recent studies have provided important insights into how several of the many phosphatase regulators, through their interaction with a conserved phosphatase catalytic subunit, control the activity of critical substrates in these diverse pathways. Recent co-crystal structures provided a major insight into how the diverse protein serine/threonine regulators rein in the otherwise promiscuous catalytic subunits.
Duke Scholars
Published In
Curr Opin Cell Biol
DOI
ISSN
0955-0674
Publication Date
April 2005
Volume
17
Issue
2
Start / End Page
197 / 202
Location
England
Related Subject Headings
- Protein Structure, Tertiary
- Phosphoprotein Phosphatases
- Models, Molecular
- Intracellular Signaling Peptides and Proteins
- Humans
- Developmental Biology
- Crystallography, X-Ray
- Circadian Rhythm
- Cell Transformation, Neoplastic
- Cell Death
Citation
APA
Chicago
ICMJE
MLA
NLM
Gallego, M., & Virshup, D. M. (2005). Protein serine/threonine phosphatases: life, death, and sleeping. Curr Opin Cell Biol, 17(2), 197–202. https://doi.org/10.1016/j.ceb.2005.01.002
Gallego, Monica, and David M. Virshup. “Protein serine/threonine phosphatases: life, death, and sleeping.” Curr Opin Cell Biol 17, no. 2 (April 2005): 197–202. https://doi.org/10.1016/j.ceb.2005.01.002.
Gallego M, Virshup DM. Protein serine/threonine phosphatases: life, death, and sleeping. Curr Opin Cell Biol. 2005 Apr;17(2):197–202.
Gallego, Monica, and David M. Virshup. “Protein serine/threonine phosphatases: life, death, and sleeping.” Curr Opin Cell Biol, vol. 17, no. 2, Apr. 2005, pp. 197–202. Pubmed, doi:10.1016/j.ceb.2005.01.002.
Gallego M, Virshup DM. Protein serine/threonine phosphatases: life, death, and sleeping. Curr Opin Cell Biol. 2005 Apr;17(2):197–202.
Published In
Curr Opin Cell Biol
DOI
ISSN
0955-0674
Publication Date
April 2005
Volume
17
Issue
2
Start / End Page
197 / 202
Location
England
Related Subject Headings
- Protein Structure, Tertiary
- Phosphoprotein Phosphatases
- Models, Molecular
- Intracellular Signaling Peptides and Proteins
- Humans
- Developmental Biology
- Crystallography, X-Ray
- Circadian Rhythm
- Cell Transformation, Neoplastic
- Cell Death