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Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.

Publication ,  Journal Article
Freedman, NJ; Lefkowitz, RJ
Published in: J Clin Invest
May 2004

Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.

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Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

May 2004

Volume

113

Issue

10

Start / End Page

1379 / 1382

Location

United States

Related Subject Headings

  • Receptors, Adrenergic, beta-1
  • Myocardium
  • Models, Cardiovascular
  • Immunology
  • Humans
  • Heart Failure
  • Autoantibodies
  • Adrenergic beta-Antagonists
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
 

Citation

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Freedman, N. J., & Lefkowitz, R. J. (2004). Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. J Clin Invest, 113(10), 1379–1382. https://doi.org/10.1172/JCI21748
Freedman, Neil J., and Robert J. Lefkowitz. “Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.J Clin Invest 113, no. 10 (May 2004): 1379–82. https://doi.org/10.1172/JCI21748.
Freedman NJ, Lefkowitz RJ. Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. J Clin Invest. 2004 May;113(10):1379–82.
Freedman, Neil J., and Robert J. Lefkowitz. “Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.J Clin Invest, vol. 113, no. 10, May 2004, pp. 1379–82. Pubmed, doi:10.1172/JCI21748.
Freedman NJ, Lefkowitz RJ. Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation. J Clin Invest. 2004 May;113(10):1379–1382.

Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

May 2004

Volume

113

Issue

10

Start / End Page

1379 / 1382

Location

United States

Related Subject Headings

  • Receptors, Adrenergic, beta-1
  • Myocardium
  • Models, Cardiovascular
  • Immunology
  • Humans
  • Heart Failure
  • Autoantibodies
  • Adrenergic beta-Antagonists
  • 42 Health sciences
  • 32 Biomedical and clinical sciences