Skip to main content
Journal cover image

Optimized MR imaging for polyacrylamide gel dosimetry.

Publication ,  Journal Article
Baustert, IC; Oldham, M; Smith, TA; Hayes, C; Webb, S; Leach, MO
Published in: Phys Med Biol
April 2000

Polyacrylamide gels are a powerful tool to measure radiation dose by quantifying the NMR T2 relaxation times of the irradiated gel. The exploitation of these radiation sensitive gels in clinical radiotherapy requires accurate mapping of T2 values. This paper describes the optimization strategy used to identify accurate and practical methods of measuring the range of T2 values typical of gel dosimeters (140-700 ms). The MR imaging techniques used to measure T2 values and the choice of image acquisition parameters are described. Four sequences are compared and the results are analysed in terms of accuracy, signal-to-noise ratio and acquisition time. A multiple spin echo sequence was found to yield the most accurate results (98.9%). Single spin echo sequences, such as Hahn spin echo and EPI spin echo, were found to measure gel T2 values with an accuracy of 90.1%. This paper reports the importance of careful selection and optimization of the MR imaging sequences for accurate and reliable polyacrylamide gel dosimetry.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

April 2000

Volume

45

Issue

4

Start / End Page

847 / 858

Location

England

Related Subject Headings

  • Time Factors
  • Radiometry
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Electrophoresis, Polyacrylamide Gel
  • Echo-Planar Imaging
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Baustert, I. C., Oldham, M., Smith, T. A., Hayes, C., Webb, S., & Leach, M. O. (2000). Optimized MR imaging for polyacrylamide gel dosimetry. Phys Med Biol, 45(4), 847–858. https://doi.org/10.1088/0031-9155/45/4/303
Baustert, I. C., M. Oldham, T. A. Smith, C. Hayes, S. Webb, and M. O. Leach. “Optimized MR imaging for polyacrylamide gel dosimetry.Phys Med Biol 45, no. 4 (April 2000): 847–58. https://doi.org/10.1088/0031-9155/45/4/303.
Baustert IC, Oldham M, Smith TA, Hayes C, Webb S, Leach MO. Optimized MR imaging for polyacrylamide gel dosimetry. Phys Med Biol. 2000 Apr;45(4):847–58.
Baustert, I. C., et al. “Optimized MR imaging for polyacrylamide gel dosimetry.Phys Med Biol, vol. 45, no. 4, Apr. 2000, pp. 847–58. Pubmed, doi:10.1088/0031-9155/45/4/303.
Baustert IC, Oldham M, Smith TA, Hayes C, Webb S, Leach MO. Optimized MR imaging for polyacrylamide gel dosimetry. Phys Med Biol. 2000 Apr;45(4):847–858.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

April 2000

Volume

45

Issue

4

Start / End Page

847 / 858

Location

England

Related Subject Headings

  • Time Factors
  • Radiometry
  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Spectroscopy
  • Electrophoresis, Polyacrylamide Gel
  • Echo-Planar Imaging
  • 5105 Medical and biological physics
  • 1103 Clinical Sciences
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences