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Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter.

Publication ,  Journal Article
McJury, M; Tapper, PD; Cosgrove, VP; Murphy, PS; Griffin, S; Leach, MO; Webb, S; Oldham, M
Published in: Phys Med Biol
October 1999

It is well known that the experimental dosimetry of brachytherapy sources presents a challenge. Depending on the particular-dosimeter used, measurements can suffer from poor spatial resolution (ion chambers), lack of 3D information (film) or errors due to the presence of the dosimeter itself distorting the radiation flux. To avoid these problems, we have investigated the dosimetry of a clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Experimental measurements of dose versus radial distance from the centre of the source (cross-line plots) were compared with calculations produced with a Nucletron NPS planning system. Good agreement was found between the planning system and gel measurements in planes selected for analysis. Gel dosimeter measurements in a coronal plane through the phantom showed a mean difference between measured absorbed dose and calculated dose of 0.17 Gy with SD = 0.13 Gy. Spatially, the errors at the reference point remain within one image pixel (1.0 mm). The use of polymer gel dosimetry shows promise for brachytherapy applications, offering complete, three-dimensional dose information, good spatial resolution and small measurement errors. Measurements close to the source, however, are difficult, due to some of the limiting properties of the polyacrylamide gel.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

October 1999

Volume

44

Issue

10

Start / End Page

2431 / 2444

Location

England

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Iridium Radioisotopes
  • Gels
  • Calibration
  • Brachytherapy
 

Citation

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McJury, M., Tapper, P. D., Cosgrove, V. P., Murphy, P. S., Griffin, S., Leach, M. O., … Oldham, M. (1999). Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Phys Med Biol, 44(10), 2431–2444. https://doi.org/10.1088/0031-9155/44/10/305
McJury, M., P. D. Tapper, V. P. Cosgrove, P. S. Murphy, S. Griffin, M. O. Leach, S. Webb, and M. Oldham. “Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter.Phys Med Biol 44, no. 10 (October 1999): 2431–44. https://doi.org/10.1088/0031-9155/44/10/305.
McJury M, Tapper PD, Cosgrove VP, Murphy PS, Griffin S, Leach MO, et al. Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Phys Med Biol. 1999 Oct;44(10):2431–44.
McJury, M., et al. “Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter.Phys Med Biol, vol. 44, no. 10, Oct. 1999, pp. 2431–44. Pubmed, doi:10.1088/0031-9155/44/10/305.
McJury M, Tapper PD, Cosgrove VP, Murphy PS, Griffin S, Leach MO, Webb S, Oldham M. Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Phys Med Biol. 1999 Oct;44(10):2431–2444.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

October 1999

Volume

44

Issue

10

Start / End Page

2431 / 2444

Location

England

Related Subject Headings

  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Iridium Radioisotopes
  • Gels
  • Calibration
  • Brachytherapy