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Optical-CT imaging of complex 3D dose distributions.

Publication ,  Journal Article
Oldham, M; Kim, L; Hugo, G
Published in: J Phys Conf Ser
April 2005

The limitations of conventional dosimeters restrict the comprehensiveness of verification that can be performed for advanced radiation treatments presenting an immediate and substantial problem for clinics attempting to implement these techniques. In essence, the rapid advances in the technology of radiation delivery have not been paralleled by corresponding advances in the ability to verify these treatments. Optical-CT gel-dosimetry is a relatively new technique with potential to address this imbalance by providing high resolution 3D dose maps in polymer and radiochromic gel dosimeters. We have constructed a 1(st) generation optical-CT scanner capable of high resolution 3D dosimetry and applied it to a number of simple and increasingly complex dose distributions including intensity-modulated-radiation-therapy (IMRT). Prior to application to IMRT, the robustness of optical-CT gel dosimetry was investigated on geometry and variable attenuation phantoms. Physical techniques and image processing methods were developed to minimize deleterious effects of refraction, reflection, and scattered laser light. Here we present results of investigations into achieving accurate high-resolution 3D dosimetry with optical-CT, and show clinical examples of 3D IMRT dosimetry verification. In conclusion, optical-CT gel dosimetry can provide high resolution 3D dose maps that greatly facilitate comprehensive verification of complex 3D radiation treatments. Good agreement was observed at high dose levels (>50%) between planned and measured dose distributions. Some systematic discrepancies were observed however (rms discrepancy 3% at high dose levels) indicating further work is required to eliminate confounding factors presently compromising the accuracy of optical-CT 3D gel-dosimetry.

Duke Scholars

Published In

J Phys Conf Ser

DOI

ISSN

1742-6588

Publication Date

April 2005

Volume

5745

Start / End Page

138 / 146

Location

England

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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Oldham, M., Kim, L., & Hugo, G. (2005). Optical-CT imaging of complex 3D dose distributions. J Phys Conf Ser, 5745, 138–146. https://doi.org/10.1117/12.595525
Oldham, Mark, Leonard Kim, and Geoffrey Hugo. “Optical-CT imaging of complex 3D dose distributions.J Phys Conf Ser 5745 (April 2005): 138–46. https://doi.org/10.1117/12.595525.
Oldham M, Kim L, Hugo G. Optical-CT imaging of complex 3D dose distributions. J Phys Conf Ser. 2005 Apr;5745:138–46.
Oldham, Mark, et al. “Optical-CT imaging of complex 3D dose distributions.J Phys Conf Ser, vol. 5745, Apr. 2005, pp. 138–46. Pubmed, doi:10.1117/12.595525.
Oldham M, Kim L, Hugo G. Optical-CT imaging of complex 3D dose distributions. J Phys Conf Ser. 2005 Apr;5745:138–146.
Journal cover image

Published In

J Phys Conf Ser

DOI

ISSN

1742-6588

Publication Date

April 2005

Volume

5745

Start / End Page

138 / 146

Location

England

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics