Castleman's disease confined to the leptomeninges.
Publication
, Journal Article
Cummings, TJ; Gong, JZ; Friedman, AH; McLendon, RE
Published in: Ann Clin Lab Sci
July 2000
We report a rare case of the plasma cell variant of Castleman's disease confined to the leptomeninges in a 42-year-old female. Flow cytometry demonstrated a minor monoclonal kappa light chain population, and conventional Southern blotting confirmed clonal rearrangement of the J(H) immunoglobulin heavy-chain gene. Polymerase chain reaction for Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus was negative. The patient is disease-free five years after surgical resection. To our knowledge, clonal gene rearrangement has not been previously reported in the plasma cell variant of localized intracranial Castleman's disease.
Duke Scholars
Published In
Ann Clin Lab Sci
ISSN
0091-7370
Publication Date
July 2000
Volume
30
Issue
3
Start / End Page
278 / 282
Location
United States
Related Subject Headings
- Middle Aged
- Immunoglobulin kappa-Chains
- Humans
- General Clinical Medicine
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Female
- Castleman Disease
- Arachnoid
- 3202 Clinical sciences
- 1103 Clinical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Cummings, T. J., Gong, J. Z., Friedman, A. H., & McLendon, R. E. (2000). Castleman's disease confined to the leptomeninges. Ann Clin Lab Sci, 30(3), 278–282.
Cummings, T. J., J. Z. Gong, A. H. Friedman, and R. E. McLendon. “Castleman's disease confined to the leptomeninges.” Ann Clin Lab Sci 30, no. 3 (July 2000): 278–82.
Cummings TJ, Gong JZ, Friedman AH, McLendon RE. Castleman's disease confined to the leptomeninges. Ann Clin Lab Sci. 2000 Jul;30(3):278–82.
Cummings, T. J., et al. “Castleman's disease confined to the leptomeninges.” Ann Clin Lab Sci, vol. 30, no. 3, July 2000, pp. 278–82.
Cummings TJ, Gong JZ, Friedman AH, McLendon RE. Castleman's disease confined to the leptomeninges. Ann Clin Lab Sci. 2000 Jul;30(3):278–282.
Published In
Ann Clin Lab Sci
ISSN
0091-7370
Publication Date
July 2000
Volume
30
Issue
3
Start / End Page
278 / 282
Location
United States
Related Subject Headings
- Middle Aged
- Immunoglobulin kappa-Chains
- Humans
- General Clinical Medicine
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Female
- Castleman Disease
- Arachnoid
- 3202 Clinical sciences
- 1103 Clinical Sciences