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Malignant melanoma presenting as a mediastinal mass.

Publication ,  Journal Article
Lau, CL; Bentley, RC; Gockerman, JP; Que, LG; D'Amico, TA
Published in: Ann Thorac Surg
March 1999
Published version (DOI) Link to item

A case of malignant melanoma presenting as a mediastinal mass without an extrathoracic primary is reported. Microscopically the tumor appeared consistent with malignant melanoma, with the presence of focal melanin pigment in large epithelioid cells. Fontana stain confirmed the presence of melanin pigment. Immunohistochemical staining further suggested melanoma, with the tumor cells expressing a HMB45+, S100+ and cytokeratin-phenotype. Electron microscopy showed an abundance of melanosomes confirming the diagnosis of malignant melanoma.

Duke Scholars

Rex Colle Bentley
Author Rex Colle Bentley Pathology
Jon Paul Gockerman
Author Jon Paul Gockerman Medicine, Hematologic Malignancies and Cellular Therapy
Loretta Georgina Que
Author Loretta Georgina Que Medicine, Pulmonary, Allergy, and Critical Care Medicine
Thomas Anthony D'Amico
Author Thomas Anthony D'Amico Surgery, Cardiovascular and Thoracic Surgery

Published In

Ann Thorac Surg

DOI

10.1016/s0003-4975(99)00075-2

ISSN

0003-4975

Publication Date

March 1999

Volume

67

Issue

3

Start / End Page

851 / 852

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Radiography
  • Melanoma
  • Mediastinal Neoplasms
  • Immunohistochemistry
  • Humans
  • Female
  • Aged
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lau, C. L., Bentley, R. C., Gockerman, J. P., Que, L. G., & D’Amico, T. A. (1999). Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg, 67(3), 851–852. https://doi.org/10.1016/s0003-4975(99)00075-2
Lau, C. L., R. C. Bentley, J. P. Gockerman, L. G. Que, and T. A. D’Amico. “Malignant melanoma presenting as a mediastinal mass.” Ann Thorac Surg 67, no. 3 (March 1999): 851–52. https://doi.org/10.1016/s0003-4975(99)00075-2.
Lau CL, Bentley RC, Gockerman JP, Que LG, D’Amico TA. Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg. 1999 Mar;67(3):851–2.
Lau, C. L., et al. “Malignant melanoma presenting as a mediastinal mass.” Ann Thorac Surg, vol. 67, no. 3, Mar. 1999, pp. 851–52. Pubmed, doi:10.1016/s0003-4975(99)00075-2.
Lau CL, Bentley RC, Gockerman JP, Que LG, D’Amico TA. Malignant melanoma presenting as a mediastinal mass. Ann Thorac Surg. 1999 Mar;67(3):851–852.
Journal cover image

Published In

Ann Thorac Surg

DOI

10.1016/s0003-4975(99)00075-2

ISSN

0003-4975

Publication Date

March 1999

Volume

67

Issue

3

Start / End Page

851 / 852

Location

Netherlands

Related Subject Headings

  • Respiratory System
  • Radiography
  • Melanoma
  • Mediastinal Neoplasms
  • Immunohistochemistry
  • Humans
  • Female
  • Aged
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology