Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data.
Publication
, Journal Article
Allen, AS; Collins, JS; Rathouz, PJ; Selander, CL; Satten, GA
Published in: BMC Genet
December 31, 2003
Informative missingness of parental genotype data occurs when the genotype of a parent influences the probability of the parent's genotype data being observed. Informative missingness can occur in a number of plausible ways and can affect both the validity and power of procedures that assume the data are missing at random (MAR). We propose a bootstrap calibration of MAR procedures to account for informative missingness and apply our methodology to refine the approach implemented in the TRANSMIT program. We illustrate this approach by applying it to data on hypertensive probands and their parents who participated in the Framingham Heart Study.
Duke Scholars
Published In
BMC Genet
DOI
EISSN
1471-2156
Publication Date
December 31, 2003
Volume
4 Suppl 1
Issue
Suppl 1
Start / End Page
S39
Location
England
Related Subject Headings
- Software
- Quantitative Trait, Heritable
- Parents
- Models, Statistical
- Male
- Humans
- Genotype
- Genetics & Heredity
- Female
- Factor Analysis, Statistical
Citation
APA
Chicago
ICMJE
MLA
NLM
Allen, A. S., Collins, J. S., Rathouz, P. J., Selander, C. L., & Satten, G. A. (2003). Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data. BMC Genet, 4 Suppl 1(Suppl 1), S39. https://doi.org/10.1186/1471-2156-4-S1-S39
Allen, Andrew S., Julianne S. Collins, Paul J. Rathouz, Craig L. Selander, and Glen A. Satten. “Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data.” BMC Genet 4 Suppl 1, no. Suppl 1 (December 31, 2003): S39. https://doi.org/10.1186/1471-2156-4-S1-S39.
Allen AS, Collins JS, Rathouz PJ, Selander CL, Satten GA. Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data. BMC Genet. 2003 Dec 31;4 Suppl 1(Suppl 1):S39.
Allen, Andrew S., et al. “Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data.” BMC Genet, vol. 4 Suppl 1, no. Suppl 1, Dec. 2003, p. S39. Pubmed, doi:10.1186/1471-2156-4-S1-S39.
Allen AS, Collins JS, Rathouz PJ, Selander CL, Satten GA. Bootstrap calibration of TRANSMIT for informative missingness of parental genotype data. BMC Genet. 2003 Dec 31;4 Suppl 1(Suppl 1):S39.
Published In
BMC Genet
DOI
EISSN
1471-2156
Publication Date
December 31, 2003
Volume
4 Suppl 1
Issue
Suppl 1
Start / End Page
S39
Location
England
Related Subject Headings
- Software
- Quantitative Trait, Heritable
- Parents
- Models, Statistical
- Male
- Humans
- Genotype
- Genetics & Heredity
- Female
- Factor Analysis, Statistical