Intranuclear inclusions in Bence Jones lambda plasma cell myeloma.
Publication
, Journal Article
Cohen, HJ; Lefer, LG
Published in: Blood
January 1975
A patient with plasma cell myeloma producing only Bence Jones lambda protein was found to have pale intranuclear inclusions in the majority of the bone marrow plasma cells. These inclusions, previously undescribed in myeloma patients producing only Bence Jones protein, contained Bence Jones lambda protein, were non-electron dense, bound by a single membrane, and contained no cytoplasmic structures. Intracytoplasmic inclusions were not present, and the perinuclear cistern was not dilated. Thus, the inclusions may represent intranuclear protein synthesis with anomalous release in the abnormal cells.
Duke Scholars
Published In
Blood
ISSN
0006-4971
Publication Date
January 1975
Volume
45
Issue
1
Start / End Page
131 / 139
Location
United States
Related Subject Headings
- Multiple Myeloma
- Middle Aged
- Male
- Immunology
- Humans
- Cell Nucleus
- Bone Marrow
- Bence Jones Protein
- 3213 Paediatrics
- 3201 Cardiovascular medicine and haematology
Citation
APA
Chicago
ICMJE
MLA
NLM
Cohen, H. J., & Lefer, L. G. (1975). Intranuclear inclusions in Bence Jones lambda plasma cell myeloma. Blood, 45(1), 131–139.
Cohen, H. J., and L. G. Lefer. “Intranuclear inclusions in Bence Jones lambda plasma cell myeloma.” Blood 45, no. 1 (January 1975): 131–39.
Cohen HJ, Lefer LG. Intranuclear inclusions in Bence Jones lambda plasma cell myeloma. Blood. 1975 Jan;45(1):131–9.
Cohen, H. J., and L. G. Lefer. “Intranuclear inclusions in Bence Jones lambda plasma cell myeloma.” Blood, vol. 45, no. 1, Jan. 1975, pp. 131–39.
Cohen HJ, Lefer LG. Intranuclear inclusions in Bence Jones lambda plasma cell myeloma. Blood. 1975 Jan;45(1):131–139.
Published In
Blood
ISSN
0006-4971
Publication Date
January 1975
Volume
45
Issue
1
Start / End Page
131 / 139
Location
United States
Related Subject Headings
- Multiple Myeloma
- Middle Aged
- Male
- Immunology
- Humans
- Cell Nucleus
- Bone Marrow
- Bence Jones Protein
- 3213 Paediatrics
- 3201 Cardiovascular medicine and haematology