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Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease.

Publication ,  Journal Article
Telen, MJ
Published in: Hematology Am Soc Hematol Educ Program
2007

A number of lines of evidence now support the hypothesis that vaso-occlusion and several of the sequelae of sickle cell disease (SCD) arise, at least in part, from adhesive interactions of sickle red blood cells, leukocytes, and the endothelium. Both experimental and genetic evidence provide support for the importance of these interactions. It is likely that future therapies for SCD might target one or more of these interactions.

Duke Scholars

Published In

Hematology Am Soc Hematol Educ Program

DOI

ISSN

1520-4391

Publication Date

2007

Start / End Page

84 / 90

Location

United States

Related Subject Headings

  • Humans
  • Endothelium, Vascular
  • Cell Adhesion Molecules
  • Anti-Inflammatory Agents
  • Anemia, Sickle Cell
 

Citation

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MLA
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Telen, M. J. (2007). Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease. Hematology Am Soc Hematol Educ Program, 84–90. https://doi.org/10.1182/asheducation-2007.1.84
Telen, Marilyn J. “Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease.Hematology Am Soc Hematol Educ Program, 2007, 84–90. https://doi.org/10.1182/asheducation-2007.1.84.
Telen MJ. Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease. Hematology Am Soc Hematol Educ Program. 2007;84–90.
Telen, Marilyn J. “Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease.Hematology Am Soc Hematol Educ Program, 2007, pp. 84–90. Pubmed, doi:10.1182/asheducation-2007.1.84.
Telen MJ. Role of adhesion molecules and vascular endothelium in the pathogenesis of sickle cell disease. Hematology Am Soc Hematol Educ Program. 2007;84–90.

Published In

Hematology Am Soc Hematol Educ Program

DOI

ISSN

1520-4391

Publication Date

2007

Start / End Page

84 / 90

Location

United States

Related Subject Headings

  • Humans
  • Endothelium, Vascular
  • Cell Adhesion Molecules
  • Anti-Inflammatory Agents
  • Anemia, Sickle Cell