Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).
Publication
, Journal Article
Taylor, GA; Feng, CG; Sher, A
Published in: Microbes Infect
2007
IRG proteins (also known as p47 GTPases) are key mediators of interferon-gamma-induced resistance to pathogens. Absence of certain IRG proteins leads to profound susceptibility to protozoa and bacteria in mice. Underlying their roles in host resistance, IRG proteins regulate the processing of pathogen-containing vacuoles in host cells, and regulate hematopoiesis following infection.
Duke Scholars
Published In
Microbes Infect
DOI
ISSN
1286-4579
Publication Date
2007
Volume
9
Issue
14-15
Start / End Page
1644 / 1651
Location
France
Related Subject Headings
- Protozoan Infections
- Microbiology
- Mice, Knockout
- Mice
- Macrophages
- Interferon-gamma
- Immunity, Innate
- Humans
- Host-Pathogen Interactions
- GTP Phosphohydrolases
Citation
APA
Chicago
ICMJE
MLA
NLM
Taylor, G. A., Feng, C. G., & Sher, A. (2007). Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). Microbes Infect, 9(14–15), 1644–1651. https://doi.org/10.1016/j.micinf.2007.09.004
Taylor, Gregory A., Carl G. Feng, and Alan Sher. “Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).” Microbes Infect 9, no. 14–15 (2007): 1644–51. https://doi.org/10.1016/j.micinf.2007.09.004.
Taylor GA, Feng CG, Sher A. Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). Microbes Infect. 2007;9(14–15):1644–51.
Taylor, Gregory A., et al. “Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).” Microbes Infect, vol. 9, no. 14–15, 2007, pp. 1644–51. Pubmed, doi:10.1016/j.micinf.2007.09.004.
Taylor GA, Feng CG, Sher A. Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). Microbes Infect. 2007;9(14–15):1644–1651.
Published In
Microbes Infect
DOI
ISSN
1286-4579
Publication Date
2007
Volume
9
Issue
14-15
Start / End Page
1644 / 1651
Location
France
Related Subject Headings
- Protozoan Infections
- Microbiology
- Mice, Knockout
- Mice
- Macrophages
- Interferon-gamma
- Immunity, Innate
- Humans
- Host-Pathogen Interactions
- GTP Phosphohydrolases