Skip to main content
Journal cover image

Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).

Publication ,  Journal Article
Taylor, GA; Feng, CG; Sher, A
Published in: Microbes Infect
2007

IRG proteins (also known as p47 GTPases) are key mediators of interferon-gamma-induced resistance to pathogens. Absence of certain IRG proteins leads to profound susceptibility to protozoa and bacteria in mice. Underlying their roles in host resistance, IRG proteins regulate the processing of pathogen-containing vacuoles in host cells, and regulate hematopoiesis following infection.

Duke Scholars

Published In

Microbes Infect

DOI

ISSN

1286-4579

Publication Date

2007

Volume

9

Issue

14-15

Start / End Page

1644 / 1651

Location

France

Related Subject Headings

  • Protozoan Infections
  • Microbiology
  • Mice, Knockout
  • Mice
  • Macrophages
  • Interferon-gamma
  • Immunity, Innate
  • Humans
  • Host-Pathogen Interactions
  • GTP Phosphohydrolases
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Taylor, G. A., Feng, C. G., & Sher, A. (2007). Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). Microbes Infect, 9(14–15), 1644–1651. https://doi.org/10.1016/j.micinf.2007.09.004
Taylor, Gregory A., Carl G. Feng, and Alan Sher. “Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).Microbes Infect 9, no. 14–15 (2007): 1644–51. https://doi.org/10.1016/j.micinf.2007.09.004.
Taylor, Gregory A., et al. “Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases).Microbes Infect, vol. 9, no. 14–15, 2007, pp. 1644–51. Pubmed, doi:10.1016/j.micinf.2007.09.004.
Journal cover image

Published In

Microbes Infect

DOI

ISSN

1286-4579

Publication Date

2007

Volume

9

Issue

14-15

Start / End Page

1644 / 1651

Location

France

Related Subject Headings

  • Protozoan Infections
  • Microbiology
  • Mice, Knockout
  • Mice
  • Macrophages
  • Interferon-gamma
  • Immunity, Innate
  • Humans
  • Host-Pathogen Interactions
  • GTP Phosphohydrolases