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Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension.

Publication ,  Journal Article
Burker, EJ; Fredrikson, M; Rifai, N; Siegel, W; Blumenthal, JA
Published in: Behav Med
1994

In this study, we examined the relation between serum lipid levels, gender, and cardiovascular and neuroendocrine stress reactivity in patients with mild hypertension. Ninety-nine individuals (62 men, 37 women) with mild hypertension performed four mental stress tasks: mental arithmetic, public speaking, cold stress, and a computer videogame. Cardiovascular reactivity scores were computed by subtracting the minimum resting blood pressure (BP) and heart rate (HR) values from the maximum values obtained during each task. Neuroendocrine reactivity was calculated as the change from epinephrine and norepinephrine values from mean rest to mean task. High and low reactors were identified on the basis of median splits of reactivity scores, averaged across all four stressors. High systolic blood pressure reactors had higher levels of total (TC), low-density lipoprotein cholesterol (LDL-C), and apo-B than did low reactors. High diastolic blood pressure reactors had lower levels of high-density lipoprotein cholesterol (HDL-C) and higher levels of LDL-C and apo-B than did low reactors. High HR reactors had higher apo-AI:apo-AII ratios than low reactors. Lipid levels were not different for high and low epinephrine and norepinephrine reactors. Although women were noted to have more favorable lipid profiles than men, both male and female hypertensive patients who were high reactors had less favorable lipid profiles than low reactors.

Duke Scholars

Published In

Behav Med

DOI

ISSN

0896-4289

Publication Date

1994

Volume

19

Issue

4

Start / End Page

155 / 161

Location

United States

Related Subject Headings

  • Sex Factors
  • Public Health
  • Norepinephrine
  • Neurosecretory Systems
  • Middle Aged
  • Male
  • Lipids
  • Hypertension
  • Humans
  • Hemodynamics
 

Citation

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MLA
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Burker, E. J., Fredrikson, M., Rifai, N., Siegel, W., & Blumenthal, J. A. (1994). Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension. Behav Med, 19(4), 155–161. https://doi.org/10.1080/08964289.1994.9935186
Burker, E. J., M. Fredrikson, N. Rifai, W. Siegel, and J. A. Blumenthal. “Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension.Behav Med 19, no. 4 (1994): 155–61. https://doi.org/10.1080/08964289.1994.9935186.
Burker EJ, Fredrikson M, Rifai N, Siegel W, Blumenthal JA. Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension. Behav Med. 1994;19(4):155–61.
Burker, E. J., et al. “Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension.Behav Med, vol. 19, no. 4, 1994, pp. 155–61. Pubmed, doi:10.1080/08964289.1994.9935186.
Burker EJ, Fredrikson M, Rifai N, Siegel W, Blumenthal JA. Serum lipids, neuroendocrine, and cardiovascular responses to stress in men and women with mild hypertension. Behav Med. 1994;19(4):155–161.
Journal cover image

Published In

Behav Med

DOI

ISSN

0896-4289

Publication Date

1994

Volume

19

Issue

4

Start / End Page

155 / 161

Location

United States

Related Subject Headings

  • Sex Factors
  • Public Health
  • Norepinephrine
  • Neurosecretory Systems
  • Middle Aged
  • Male
  • Lipids
  • Hypertension
  • Humans
  • Hemodynamics