Skip to main content
Journal cover image

Burden of pancreatic cancer and disease progression: economic analysis in the US.

Publication ,  Journal Article
Chang, S; Long, SR; Kutikova, L; Bowman, L; Crown, WH; Lyman, GH
Published in: Oncology
2006

OBJECTIVES: The few studies that have estimated the costs of pancreatic cancer were limited by small sample sizes, geography or patient age range. Using a large nationwide claims database, this study examines the cost of pancreatic cancer beginning with initial diagnosis and the additional costs when disease progresses. METHODS: A retrospective cohort study was conducted using a claims database of 3 million individuals covered by large US employers. The study population consisted of patients newly diagnosed with pancreatic cancer in 1999-2000 and a demographically matched control group. Utilization and costs were summarized as monthly means. Changes in cancer severity and treatment over time were used to approximate disease progression and its associated costs. RESULTS: The study included 412 pancreatic cancer patients and 1,236 controls. The mean follow-up time was 7.5 months. Regression-adjusted monthly costs attributable to pancreatic cancer were USD 7,279; over 60% resulted from hospitalizations. Patients with disease progression (over 50%) incurred an additional USD 15,143 per month compared to patients without disease progression. CONCLUSION: Compared to patients without cancer, the costs of pancreatic cancer patients were substantial, especially when patients experienced disease progression. New therapies that prevent or delay disease progression could potentially offset the costs to patients, providers and society.

Duke Scholars

Published In

Oncology

DOI

ISSN

0030-2414

Publication Date

2006

Volume

70

Issue

1

Start / End Page

71 / 80

Location

Switzerland

Related Subject Headings

  • United States
  • Pancreatic Neoplasms
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Female
  • Disease Progression
  • Cost of Illness
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Chang, S., Long, S. R., Kutikova, L., Bowman, L., Crown, W. H., & Lyman, G. H. (2006). Burden of pancreatic cancer and disease progression: economic analysis in the US. Oncology, 70(1), 71–80. https://doi.org/10.1159/000091312
Chang, Stella, Stacey R. Long, Lucie Kutikova, Lee Bowman, William H. Crown, and Gary H. Lyman. “Burden of pancreatic cancer and disease progression: economic analysis in the US.Oncology 70, no. 1 (2006): 71–80. https://doi.org/10.1159/000091312.
Chang S, Long SR, Kutikova L, Bowman L, Crown WH, Lyman GH. Burden of pancreatic cancer and disease progression: economic analysis in the US. Oncology. 2006;70(1):71–80.
Chang, Stella, et al. “Burden of pancreatic cancer and disease progression: economic analysis in the US.Oncology, vol. 70, no. 1, 2006, pp. 71–80. Pubmed, doi:10.1159/000091312.
Chang S, Long SR, Kutikova L, Bowman L, Crown WH, Lyman GH. Burden of pancreatic cancer and disease progression: economic analysis in the US. Oncology. 2006;70(1):71–80.
Journal cover image

Published In

Oncology

DOI

ISSN

0030-2414

Publication Date

2006

Volume

70

Issue

1

Start / End Page

71 / 80

Location

Switzerland

Related Subject Headings

  • United States
  • Pancreatic Neoplasms
  • Oncology & Carcinogenesis
  • Middle Aged
  • Male
  • Humans
  • Follow-Up Studies
  • Female
  • Disease Progression
  • Cost of Illness