Rheological properties of contraceptive gels.
Publication
, Journal Article
Owen, DH; Peters, JJ; Katz, DF
Published in: Contraception
December 2000
The rheological properties of 4 commercially available contraceptive drug delivery gels and their dilutions with a vaginal fluid simulant were measured. These properties govern the critical functions of spreading and retention of these gels over the vaginal surfaces. Measurements made on Conceptrol, KY Plus, Gynol II, and Advantage-S included stress growth, stress relaxation and residual stress, and the shear rate dependence of viscosity. All gels exhibited non-Newtonian behavior including shear thinning and viscoelasticity. Conceptrol and Gynol II had no residual stress, while both KY Plus and Advantage-S did. The gels differed in their response to dilution with vaginal fluid simulant.
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Published In
Contraception
DOI
EISSN
1879-0518
ISSN
0010-7824
Publication Date
December 2000
Volume
62
Issue
6
Start / End Page
321 / 326
Related Subject Headings
- Vagina
- Spermatocidal Agents
- Rheology
- Obstetrics & Reproductive Medicine
- Humans
- Gels
- Female
- Chemistry, Pharmaceutical
- Carboxymethylcellulose Sodium
- Body Fluids
Citation
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Chicago
ICMJE
MLA
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Owen, D. H., Peters, J. J., & Katz, D. F. (2000). Rheological properties of contraceptive gels. Contraception, 62(6), 321–326. https://doi.org/10.1016/s0010-7824(00)00184-0
Owen, D. H., J. J. Peters, and D. F. Katz. “Rheological properties of contraceptive gels.” Contraception 62, no. 6 (December 2000): 321–26. https://doi.org/10.1016/s0010-7824(00)00184-0.
Owen DH, Peters JJ, Katz DF. Rheological properties of contraceptive gels. Contraception. 2000 Dec;62(6):321–6.
Owen, D. H., et al. “Rheological properties of contraceptive gels.” Contraception, vol. 62, no. 6, Dec. 2000, pp. 321–26. Epmc, doi:10.1016/s0010-7824(00)00184-0.
Owen DH, Peters JJ, Katz DF. Rheological properties of contraceptive gels. Contraception. 2000 Dec;62(6):321–326.
Published In
Contraception
DOI
EISSN
1879-0518
ISSN
0010-7824
Publication Date
December 2000
Volume
62
Issue
6
Start / End Page
321 / 326
Related Subject Headings
- Vagina
- Spermatocidal Agents
- Rheology
- Obstetrics & Reproductive Medicine
- Humans
- Gels
- Female
- Chemistry, Pharmaceutical
- Carboxymethylcellulose Sodium
- Body Fluids