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Factors influencing the participation of gastroenterologists and hepatologists in clinical research.

Publication ,  Journal Article
Dev, AT; Kauf, TL; Zekry, A; Patel, K; Heller, K; Schulman, KA; McHutchison, JG
Published in: BMC Health Serv Res
October 8, 2008

BACKGROUND: Although clinical research is integral to the advancement of medical knowledge, physicians face a variety of obstacles to their participation as investigators in clinical trials. We examined factors that influence the participation of gastroenterologists and hepatologists in clinical research. METHODS: We surveyed 1050 members of the American Association for the Study of Liver Diseases regarding their participation in clinical research. We compared the survey responses by specialty and level of clinical trial experience. RESULTS: A majority of the respondents (71.6%) reported involvement in research activities. Factors most influential in clinical trial participation included funding and compensation (88.3%) and intellectual pursuit (87.8%). Barriers to participation were similar between gastroenterologists (n = 160) and hepatologists (n = 189) and between highly experienced (n = 62) and less experienced (n = 159) clinical researchers. These barriers included uncompensated research costs and lack of specialized support. Industry marketing was a greater influence among respondents with less trial experience, compared to those with extensive experience (15.7% vs 1.6%; P < .01). Hepatologists and respondents with extensive clinical trial experience tended to be more interested in phase 1 and 2 studies, whereas gastroenterologists and less experienced investigators were more interested in phase 4 studies. CONCLUSION: This study suggests that the greatest barrier to participation in clinical research is lack of adequate resources. Respondents also favored industry-sponsored research with less complex trial protocols and studies of relatively short duration.

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Published In

BMC Health Serv Res

DOI

EISSN

1472-6963

Publication Date

October 8, 2008

Volume

8

Start / End Page

208

Location

England

Related Subject Headings

  • United States
  • Surveys and Questionnaires
  • Ribavirin
  • Research Support as Topic
  • Physicians
  • Middle Aged
  • Male
  • Liver Cirrhosis
  • Interferons
  • Humans
 

Citation

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Dev, A. T., Kauf, T. L., Zekry, A., Patel, K., Heller, K., Schulman, K. A., & McHutchison, J. G. (2008). Factors influencing the participation of gastroenterologists and hepatologists in clinical research. BMC Health Serv Res, 8, 208. https://doi.org/10.1186/1472-6963-8-208
Dev, Anouk T., Teresa L. Kauf, Amany Zekry, Keyur Patel, Karen Heller, Kevin A. Schulman, and John G. McHutchison. “Factors influencing the participation of gastroenterologists and hepatologists in clinical research.BMC Health Serv Res 8 (October 8, 2008): 208. https://doi.org/10.1186/1472-6963-8-208.
Dev AT, Kauf TL, Zekry A, Patel K, Heller K, Schulman KA, et al. Factors influencing the participation of gastroenterologists and hepatologists in clinical research. BMC Health Serv Res. 2008 Oct 8;8:208.
Dev, Anouk T., et al. “Factors influencing the participation of gastroenterologists and hepatologists in clinical research.BMC Health Serv Res, vol. 8, Oct. 2008, p. 208. Pubmed, doi:10.1186/1472-6963-8-208.
Dev AT, Kauf TL, Zekry A, Patel K, Heller K, Schulman KA, McHutchison JG. Factors influencing the participation of gastroenterologists and hepatologists in clinical research. BMC Health Serv Res. 2008 Oct 8;8:208.
Journal cover image

Published In

BMC Health Serv Res

DOI

EISSN

1472-6963

Publication Date

October 8, 2008

Volume

8

Start / End Page

208

Location

England

Related Subject Headings

  • United States
  • Surveys and Questionnaires
  • Ribavirin
  • Research Support as Topic
  • Physicians
  • Middle Aged
  • Male
  • Liver Cirrhosis
  • Interferons
  • Humans