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Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.

Publication ,  Journal Article
Diaz, GC; Prowda, J; Lo, IJ; Arepally, GM; Evans, N; Wheeless, Y; Samstein, B; Guarrera, JV; Renz, JF
Published in: Liver Transpl
December 2008

Transplantation-mediated alloimmune thrombocytopenia (TMAT) is donor-derived thrombocytopenia following solid-organ transplantation. To date, no clear consensus on the appropriateness of organ utilization from cadaver donors with a history of idiopathic thrombocytopenia purpura (ITP) has emerged. Herein is reported a devastating case of TMAT following liver transplantation utilizing an allograft from a donor with ITP that resulted in allograft failure. The literature is reviewed in this context to propose preliminary guidelines regarding utilization of allografts from cadaver donors with a history of ITP.

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Published In

Liver Transpl

DOI

EISSN

1527-6473

Publication Date

December 2008

Volume

14

Issue

12

Start / End Page

1803 / 1809

Location

United States

Related Subject Headings

  • Tissue Donors
  • Thrombocytopenia
  • Surgery
  • Radiography
  • Purpura, Thrombocytopenic, Idiopathic
  • Practice Guidelines as Topic
  • Postoperative Complications
  • Middle Aged
  • Male
  • Liver Transplantation
 

Citation

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Diaz, G. C., Prowda, J., Lo, I. J., Arepally, G. M., Evans, N., Wheeless, Y., … Renz, J. F. (2008). Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors. Liver Transpl, 14(12), 1803–1809. https://doi.org/10.1002/lt.21539
Diaz, Geraldine C., Joan Prowda, Irene J. Lo, Gowthami M. Arepally, Neal Evans, Yvonne Wheeless, Benjamin Samstein, James V. Guarrera, and John F. Renz. “Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.Liver Transpl 14, no. 12 (December 2008): 1803–9. https://doi.org/10.1002/lt.21539.
Diaz GC, Prowda J, Lo IJ, Arepally GM, Evans N, Wheeless Y, et al. Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors. Liver Transpl. 2008 Dec;14(12):1803–9.
Diaz, Geraldine C., et al. “Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors.Liver Transpl, vol. 14, no. 12, Dec. 2008, pp. 1803–09. Pubmed, doi:10.1002/lt.21539.
Diaz GC, Prowda J, Lo IJ, Arepally GM, Evans N, Wheeless Y, Samstein B, Guarrera JV, Renz JF. Transplantation-mediated alloimmune thrombocytopenia: Guidelines for utilization of thrombocytopenic donors. Liver Transpl. 2008 Dec;14(12):1803–1809.
Journal cover image

Published In

Liver Transpl

DOI

EISSN

1527-6473

Publication Date

December 2008

Volume

14

Issue

12

Start / End Page

1803 / 1809

Location

United States

Related Subject Headings

  • Tissue Donors
  • Thrombocytopenia
  • Surgery
  • Radiography
  • Purpura, Thrombocytopenic, Idiopathic
  • Practice Guidelines as Topic
  • Postoperative Complications
  • Middle Aged
  • Male
  • Liver Transplantation