Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva.
Publication
, Journal Article
To, KW; Rabinowitz, SM; Friedman, AH; Merker, C; Cavanaugh, CP
Published in: Surv Ophthalmol
1989
With an occurrence of approximately 1 in 3000 births, von Recklinghausen neurofibromatosis (NF) is one of the most common inherited human disorders. NF is considered a neurocristopathy, a disorder of neural crest derived cells. One of the complications of NF is the development of neural crest derived malignancies such as malignant schwannoma, pheochromocytoma, and malignant melanoma of the skin and choroid. The case history of a patient with NF and conjunctival malignant melanoma which developed in an eye with primary acquired melanosis is yet another example of a neural crest malignancy developing in a NF patient.
Duke Scholars
Published In
Surv Ophthalmol
DOI
ISSN
0039-6257
Publication Date
1989
Volume
33
Issue
5
Start / End Page
373 / 379
Location
United States
Related Subject Headings
- Ophthalmology & Optometry
- Neurofibromatosis 1
- Neural Crest
- Middle Aged
- Melanosis
- Melanoma
- Humans
- Female
- Conjunctival Neoplasms
- Biopsy
Citation
APA
Chicago
ICMJE
MLA
NLM
To, K. W., Rabinowitz, S. M., Friedman, A. H., Merker, C., & Cavanaugh, C. P. (1989). Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva. Surv Ophthalmol, 33(5), 373–379. https://doi.org/10.1016/0039-6257(89)90014-3
To, K. W., S. M. Rabinowitz, A. H. Friedman, C. Merker, and C. P. Cavanaugh. “Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva.” Surv Ophthalmol 33, no. 5 (1989): 373–79. https://doi.org/10.1016/0039-6257(89)90014-3.
To KW, Rabinowitz SM, Friedman AH, Merker C, Cavanaugh CP. Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva. Surv Ophthalmol. 1989;33(5):373–9.
To, K. W., et al. “Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva.” Surv Ophthalmol, vol. 33, no. 5, 1989, pp. 373–79. Pubmed, doi:10.1016/0039-6257(89)90014-3.
To KW, Rabinowitz SM, Friedman AH, Merker C, Cavanaugh CP. Neurofibromatosis and neural crest neoplasms: primary acquired melanosis and malignant melanoma of the conjunctiva. Surv Ophthalmol. 1989;33(5):373–379.
Published In
Surv Ophthalmol
DOI
ISSN
0039-6257
Publication Date
1989
Volume
33
Issue
5
Start / End Page
373 / 379
Location
United States
Related Subject Headings
- Ophthalmology & Optometry
- Neurofibromatosis 1
- Neural Crest
- Middle Aged
- Melanosis
- Melanoma
- Humans
- Female
- Conjunctival Neoplasms
- Biopsy