Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes.
Publication
, Journal Article
Speciale, SG; Friedman, AH
Published in: Pharmacol Biochem Behav
1975
The duration of sleep induced by a fixed dose of gamma-butyrolactone (GBL) (350 mg/kg, IP) FOllows the normal circadian sleep pattern of rats. GBL sleep duration is maximal at 1800 hr and minimal at 0600 hr. CNS amine changes are not extensive, but when normal sleep is anticipated, GBL treatment increases dopamine and serotonin levels and decreases norepinephrine levels.
Duke Scholars
Published In
Pharmacol Biochem Behav
DOI
ISSN
0091-3057
Publication Date
1975
Volume
3
Issue
5
Start / End Page
761 / 764
Location
United States
Related Subject Headings
- Time Factors
- Sleep
- Serotonin
- Rats
- Norepinephrine
- Neurology & Neurosurgery
- Mesencephalon
- Male
- Hypothalamus
- Furans
Citation
APA
Chicago
ICMJE
MLA
NLM
Speciale, S. G., & Friedman, A. H. (1975). Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes. Pharmacol Biochem Behav, 3(5), 761–764. https://doi.org/10.1016/0091-3057(75)90103-3
Speciale, S. G., and A. H. Friedman. “Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes.” Pharmacol Biochem Behav 3, no. 5 (1975): 761–64. https://doi.org/10.1016/0091-3057(75)90103-3.
Speciale SG, Friedman AH. Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes. Pharmacol Biochem Behav. 1975;3(5):761–4.
Speciale, S. G., and A. H. Friedman. “Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes.” Pharmacol Biochem Behav, vol. 3, no. 5, 1975, pp. 761–64. Pubmed, doi:10.1016/0091-3057(75)90103-3.
Speciale SG, Friedman AH. Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes. Pharmacol Biochem Behav. 1975;3(5):761–764.
Published In
Pharmacol Biochem Behav
DOI
ISSN
0091-3057
Publication Date
1975
Volume
3
Issue
5
Start / End Page
761 / 764
Location
United States
Related Subject Headings
- Time Factors
- Sleep
- Serotonin
- Rats
- Norepinephrine
- Neurology & Neurosurgery
- Mesencephalon
- Male
- Hypothalamus
- Furans